Canine parvovirosis is a very transmissible, severe and often deadly infectious disease of dogs caused by Type II canine parvovirus (CPV-2). Recently shows that Parvoviruses are very resistant to Acyclovir which is often used for HSV Chemotherapy in humans and various virucidal purposes in animal diseases in veterinary clinics and animal housing facilities. If acquiescence with vaccination programs and with appropriate decontamination plans is guaranteed, there should be no continuous, nor common, CPV-2 outbreaks. However, a continuous spread of CPV-2 infections is observed, even in shelters where an appropriate vaccination program is applied, and this is reason to provide an antiviral drug therapy. The aim of the present study was to Development of antiviral drugs with determination the effect of concentration of new chemical entity and analyze Acyclovir analogous against CPV-2 strains. A sensitive in vitro assay capable of measuring the infectivity of CPV-2 was employed to determine the efficacy of three different concentrations of 9-(2-hydroxyethomethyl)guanine phosphoromonomorpholidate. We successfully show that new compounds inhibit CPV-2 replication with exhibiting 50% inhibitory concentrations (IC 50 s) in the low-micromolar range (50μM ).

No abstract

Cervical cancer (CC) is a worldwide disease with 97000 of new cases per year occurring in most populated country, India. The objective of this study was to find possible factors which could affect knowledge about CC and, some CC risk factors in our community. A community-based cross-sectional study was carried out in Maharashtra, State of India. Knowledge about CC is modulated by the level of education and the young age of women. Risk factors although universal seem to vary according to the geographical area and the socio-cultural environment where one lives. Some risk factors identified are early onset of sexual intercourse, polygamous marriages, multiple sexual partners, the sexual behavior of the male partner, Human papilloma virus (HPV) infections, sexually transmitted diseases (STDs), Human Deficiency Virus (HIV), and history of genital warts. No enhancement of lifestyle as the voluntary refusal of cervical cancer screening and CC vaccination have also be found to be risky attitudes for CC.

Nano-robots are the robots that are the technology of creating machines or robots close to the microscopic scale of a nanometre (10-9meters). These devices range from 0.1 – 10 micrometres. Nano-robots are the advances in technology. The technology has expanded our capability and potential to operate the world around us on above removing scale. Nano robots can be used in various application such as space and medicine technology. Nanos robots are device is used for motive of nourishing, keeping and protecting the human body opposing antibody, microorganisms, pathogens. Nano robots are instrumental by using various components such as actuators, sensors, control, power, conveying and by affiliating cross – marked scales between organic and inorganic systems. Nanotechnologies are quickly arising within the nation of medicine, and this subdivision has been termed Nano medicine. Application for nanorobotics in medicine including diagnosis and drug delivery for cancer, tissue engineering, pharmacokinetics, dental surgery, ophthalmology and others. This region of work is fulfilled with prospective and possible applications, many of like that recently animating researched and evolution. The objective of this paper is to introduce the expanding sector of nanorobotics inside in medicine and advancement in medical application.