Objective The objective of this study was to investigate clinical neurocognitive performance and microstructural white matter (WM) alterations in infants of mothers with gestational diabetes mellitus (GDM) using diffusion tensor imaging. Materials and Methods Infants (corrected gestational age, 33.42–36.00 weeks) of mothers with GDM (n = 31) and gestational age- and sex-matched unexposed controls (n = 31) accomplished 3-T diffusion tensor imaging scans and neurocognitive tests. Diffusion tensor imaging measures, mainly referring to fractional anisotropy (FA) values, were compared between 2 groups, and within-group analysis of correlation between FA values and neurocognitive testing outcomes in GDM-exposed infants was conducted subsequently. Results Fractional anisotropy was significantly decreased in the splenium of corpus callosum, posterior limb of internal capsule, thalamus in infants of mothers with GDM when compared with controls (P < 0.05), reflecting microstructural WM abnormalities in the GDM group. Decreased FA was associated with worse neurocognitive performance in the exposed group (P < 0.05). Conclusions Individuals of mothers with GDM showed microstructural WM abnormalities in different brain regions, which were significantly related to worse neurocognitive performance. This might reveal that GDM directly insults the brain development of the offspring.
Phosphorus (P) adsorpted by sediments, when covered by and mixed with ignited sediments from Meiliang Bay in Tai Lake, was analyzed in the laboratory. Potassium dihydrogen phosphate (KHPO) was added to the parallel experimental units to simulate periodic external P input. Based on the Langmuir model, the sediments after ignition had a greater S (maximum P adsorption), a lower equilibrium phosphorus concentration at zero adsorption (EPC), and a lower degree of phosphorus saturation in comparison with sediments without ignition. This was confirmed by the variation in the dissolved inorganic phosphorus in the overlying water. When sediments were mixed with or covered by the ignited sediments, 5.985 and 5.978 mg of input P disappeared from the overlying water, respectively. However, when the sediments were mixed with the ignited sediments, 84.18% of the input P was converted to HCl-P, whereas when they were covered by the ignited sediments, sedimentary P was released, mainly from Fe/Al-P (up to 87.50%). This was attributed to differences in the microenvironments where less-intense anaerobic conditions were formed in the mixed sediments than in the sediments covered by the ignited sediments. This suggests that the injection of ignited sediments into existing sediments enhances their P adsorption and retention. It is favor of the control of the eutrophication with a simple technology.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.