Chang’E-5 (CE-5) is China’s first lunar sample return mission. This paper focuses on the trajectory determination of the CE-5 lander and ascender during the landing and ascending phases, and the positioning of the CE-5 lander on the Moon. Based on the kinematic statistical orbit determination method using B-spline and polynomial functions, the descent and ascent trajectories of the lander and ascender are determined by using ground-based radiometric ranging, Doppler and interferometry data. The results show that a B-spline function is suitable for a trajectory with complex maneuvers. For a smooth trajectory, B-spline and polynomial functions can reach almost the same solutions. The positioning of the CE-5 lander on the Moon is also investigated here. Using the kinematic statistical positioning method, the landing site of the lander is 43.0590°N, 51.9208°W with an elevation of −2480.26 m, which is less than 200 m different from the LRO (Lunar Reconnaissance Orbiter) image data.
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