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Dihydropyrazole (1−22) derivatives were synthesized from already synthesized chalcones. The structures of all of the synthesized compounds were confirmed by elemental analysis and various spectroscopic techniques. Furthermore, the synthesized compounds were screened against α amylase as well as investigated for antioxidant activities. The synthesized compounds demonstrate good to excellent antioxidant activities with IC 50 values ranging between 30.03 and 913.58 μM. Among the 22 evaluated compounds, 11 compounds exhibit excellent activity relative to the standard ascorbic acid IC 50 = 287.30 μM. Interestingly, all of the evaluated compounds show good to excellent α amylase activity with IC 50 values lying in the range between 0.5509 and 810.73 μM as compared to the standard acarbose IC 50 = 73.12 μM. Among the investigated compounds, five compounds demonstrate better activity compared to the standard. In order to investigate the binding interactions of the evaluated compounds with amylase protein, molecular docking studies were conducted, which show an excellent docking score as compared to the standard. Furthermore, the physiochemical properties, drug likeness, and ADMET were investigated, and it was found that none of the compounds violate Lipiniski's rule of five, which shows that this class of compounds has enough potential to be used as a drug candidate in the near future.

A Z-scheme g-C3N4/TS-1 heterojunction supported photosensitizer, along with an Au–TiO2 energy avenue, enables selective photocatalytic CO2 reduction to CH4, CO, and H2. This innovative approach enhances green fuel production efficiency effectively.

Two series, A and B, of PVC based nanocomposite polymer membranes (nCPMs) were prepared using PbO only and PbO/graphite mixture as a filler by solution casting method. Seven samples with varying compositions (5–35%) of filler particles were prepared for each series and were compared by thickness measurements, porosity, water uptake, swelling degree, ionic conductivity, ion exchange capacity (IEC), membrane potential and transport number. The maximum values for these characteristics were observed as 0.402 mm, 0.77, 141.3%, 0.11, 0.0033 Scm−1, 8.6 milli-eq.g−1, 0.19 V and 0.01391 for series-A composites whereas that of 0.367 mm, 0.83, 63.4%, 0.019, 0.00981 Scm−1, 5.21 milli-eq.g−1, 0.13 V and 0.0108 for series-B nCPMs respectively. The SEM images of membranes showed greater voids produced in the series-B compared to series-A composites. The maximum Ionic conductivity, IEC, membrane potential and transport number were observed for membrane with 25% PbO/graphite, 20% PbO and 35% PbO particles respectively.

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