SummaryForty-five operative procedures were performed in 32 patients with Down's syndrome at the Royal Alexandra Hospital for Children, Sydney in a single year recently. Atropine premedication was administered to 25 patients with Down's syndrome on 38 occasions. Three dosage regimes of atropine were used: 2Opgglkg, 12 pgcglkg, both intramuscularly, and 10 pgglkg intravenously. There was no statistically signi$cant difference in the alteration of heart rate for the three dosage groups of atropine used when children with Down's syndrome were compared with weight-matched control children having similar operative procedures performed.

Thoracic surgery is cost intensive. With increasing staging of the tumor, the cost for treatment increased as with increased operation complexity.

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