HLA (Human Leukocyte Antigen) gene is located on chromosome 6’s short arm, including several loci. HLA genotyping is necessary for transplantation, especially in hematopoietic stem cell transplantation. A cross-sectional study to determine the frequency of HLA-A, HLA-B, and HLA-DRB1 alleles of 122 patients admitted to the National Children’s Hospital for Hematopoietic stem cell transplantation from the year between 2010 and 2020. The patients’ HLA genotyping was performed by PCR-SSP method using Micro SSPTM Generic HLA Class I and II DNA Typing Tray (One Lambda). The results showed that the HLA-A locus has 12 alleles of which the highest frequency alleles are A*11 (24.18%), A*02 (23.36%), A*33 (20.90%), and A*24 (14.34%). HLA-B locus has 24 alleles in which the highest frequency alleles are B*15 (24.59%), B*58 (12.30%), B*07 (9.02%), and B*46 (8.20%). HLA-C locus has ten alleles of which the highest frequency alleles are C*03 (24.59%), C*07 (22.12%), and C*04 (13.52%). HLA-DRB1 locus has 13 alleles of which the highest frequency alleles are DRB1*12 (23.77%), DRB1*03 (11.07%), DRB1*15 (10.25%), and DRB1*09 & DRB1*07 (8.20%). There are 1984 haplotypes combined from 4 loci HLA-A, HLA-B, HLA-C, and HLA-DRB1, of which the highest frequency haplotypes are A*11/B*15/C*08/DRB1*12 (1.21%); A*33/B*58/C*03/DRB1*03 (1.06%); A*11/B*15/C*04/DRB1*12 (0.76%); A*11/B*15/C*04/DRB1*12 (0.71%), and A*11/B*15/C*03/DRB1*12 (0.71%). The study provides the frequencies of alleles and haplotypes of HLA genotypes in Hematopoietic Stem Cell Transplantation. This is very important information for choosing stem cell donors and establishing the stem cell bank.

Chúng tôi phân tích 113 bệnh nhân u trung thất được mổ nội soi điều trị trong đó mổ nội soi hoàn toàn (101 trường hợp), mổ nội soi có hỗ trợ (12 trường hợp). Không có trường hợp nào tử vong hay chuyển mổ mở. Chúng tôi phân tích tìm mối liên hệ giữa các triệu chứng trên CT ngực (vị trí u, loại u, kích thước u, tăng tỷ trọng u sau tiêm thuốc cản quang, u chèn ép, u xâm lấn xung quanh, vôi hóa u) với kết quả sau mổ nội soi (thời gian mổ, lượng máu mất, thời gian hậu phẫu, thời gian lưu ống dẫn lưu màng phổi, điểm đau sau mổ, các biến chứng). Sau khi phân tích các mối liên hệ giữa đặc điểm u trung thất trên CT ngực với kết quả đạt được. Cho thấy phẫu thuật nội soi điều trị u trung thất tốt cho các u trung thất như: u có kích thước nhỏ, nang trung thất, u không xâm lấn, chèn ép, u ít tăng tỉ trọng sau tiêm thuốc cản quang, u không vôi hóa.

Introduction: Thoracic and abdominal aortic disease is a rare, serious disease and one of the major challenges for the surgeon with a high prognosis of complications and mortality. Surgery combined with endovascular intervention is a new, minimally invasive method with good early results and good mid-term results. Methods: We report a case diagnosed with thoracoabdominal aortic aneurysm underwent hybrid intervention at Dong Nai General Hospital Results: A 68-year-old female patient was diagnosed with Crawford Type V thoracoabdominal aortic aneurysm, underwent debranching surgery of the superior mesenteric artery and celiac trunk followed by stent graft deployment of the diseased aorta, the postoperative course was uneventful. Conclusions:  Hybrid surgery to treat thoracoabdominal aortic aneurysms can initially be performed at Dong Nai General Hospital. The implementation of this technique at provincial hospitals helps to improve prognosis, reduce mortality and complications, and contribute to improving the professional quality of the hospital.

Urban development management is a global trend, and an urgent requirement in Vietnam today. In recent years, urban development in the southwestern region along the trend of adaptation to climate change has received the attention of the Party and the State; at the same time achieve certain results. However, the management of urban development in the southwestern region adapting to climate change is still inadequate, requiring more robust, systematic and synchronized measures in the development process and urban management in the Southwest region.

Introduction: Aortic disease is a serious disease with sudden onset and high mortality. Endovascular intervention is a novel, minimally invasive method with good early and mid-term results. Subjects: We report 03 patients diagnosed with aortic disease undergoing endovascular intervention at Dong Nai general hospital. Results: 1 case of high-risk type B aortic dissection, 1 case of descending thoracic aortic aneurysm ruptured into the left lung causing hemoptysis and 1 case of symptomatic aortic arch aneurysm. 2 partial debranching of the aortic arch were performed. The recovery time of all 3 cases was 1 day. In the postoperative period, the patients quickly recovered and received physical therapy very soon. After the surgery, all patients recovered well and were able to integrate into daily life. Conclusion: Aortic endovascular intervention was successfully implemented at Dong Nai General Hospital in the initial phase. The availability of this technique at provincial hospitals improves prognosis, reduces mortality and complications, and contributes to the improvement of the hospital's professional quality.