Background: Tooth extraction is one of the most frequently performed procedures in dental practice. Resorption without bone regeneration can change the maxillary and mandibular bone structure, resulting lack of retention, stability, and comfort of the denture. Hence, adequate regeneration of alveolar bone is considered an important factor for successful dentures. Moringa oleifera is a plant rich in flavonoids, saponins, alkaloids and tannins. Purpose: This study aims to find out the effect of induction from combination of Moringa oleifera extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction procedure. Methods: Cavia cobaya was divided into eight groups, each group consists of seven. The lower incisors of Fifty-six Cavia cobaya were extracted. The first group (control group) was given polyethylene glycol, the second group with DFDBBX, the third group with Moringa leaf extract, and the fourth group with a combination of DFDBBX and Moringa leaf extract. Cavia cobaya were sacrificed on day 7 and 14. Histopathological examinations of woven bone area was observed under a 400x magnification light microscope. Kruskal-Wallis and Mann-Whitney tests were performed to analyze the data. Results: There was a significant difference in woven bone area between the groups (P<0.05). The highest mean of woven bone area was found in the combination group on both day 7 and 14. Conclusion: The combination of Moringa leaf extract and DFDBBX could effectively formed new woven bone during the alveolar bone regeneration.
Background: After tooth extraction, alveolar bone resorption occurs naturally, followed by alveolar bone remodeling. Alveolar bone formation is characterized by an increase in density and expansion of the trabecular bone. Socket preservation using a combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) is expected to increase the area of the alveolar bone trabeculae and thus accelerate the process of alveolar bone formation. Purpose: This study aimed to determine if a combination of Moringa oleifera leaf extract and DFDBBX could increase the area of the alveolar bone trabeculae in tooth extraction sockets. Methods: With their lower left incisors extracted, the 56 Cavia cobayas were divided into eight treatment groups according to the material given: polyethylene glycol (PEG), DFDBBX and PEG, Moringa oleifera leaf extract and PEG, and a combination of Moringa oleifera leaf extract, DFDBBX, and PEG. On the seventh and thirtieth days, the Cavia cobayas were sacrificed and examined. Histopathological samples were stained with Hematoxylin-Eosin (HE) to evaluate the trabecula area, and data were analyzed using one-way ANOVA and Tukey HSD. Results: On the thirtieth day, the group that received a combination of Moringa oleifera leaf extract and DFDBBX had the greatest area of alveolar bone trabeculae. Conclusion: A combination of Moringa oleifera leaf extract and DFDBBX induced in the tooth extraction socket can increase the area of the alveolar bone trabeculae.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.