No abstract

Objective: The aim of this study was to evaluate the response of treatment of central giant cell lesion to intralesional corticosteroid injections. Study Design: Review of articles indexed in PubMed on the topic between the years 1988 and 2011, and development of a descriptive meta-analysis of the results. Results: Sample of 41 patients primarily treated with intralesional corticosteroid injections was obtained, with a male female ratio of 1:0.95, being 23 aggressive and 18 non-aggressive central giant cell lesions. Triamcinolone acetonide and triamcinolone hexacetonide were the drugs used, and 78.0% cases were considered as good result, 14.6% were considered as moderate response and 7.3% were considered as negative result to treatment. Considering the aggressiveness, 88.9% of non-aggressive lesions presented a good response to treatment, in aggressive central giant cell lesions, 69.6% presented a good response to intralesional corticosteroid injections. Conclusion: In view of the results analyzed, intralesional corticosteroid injections could be considered as first treatment option for central giant cell lesion. Key words:Central giant cell lesion, corticosteroids injections, triamcinolone hexacetonide, triamcinolone acetonide.

SUMMARY -The authors describe a rare case of increased intracranial hypertension consequent to a spinal cervical glioblastoma multiforme in a young patient. They analyse the physiopathology of intracranial hypertension in spinal tumors and the rarity of such kind of tumor in this location, and its clinico-pathological aspects.K E Y WORDS: intracranial hypertension, spinal glioblastoma multiforme, young patient. Hipertensão intracraniana em caso de glioblastoma multiforme da medula cervical: análise dessas duas raras condiçõesRESUMO -Os autores descrevem um raro caso de hipertensão intracraniana conseqüente a glioblastoma multiforme situado na medula cervical de uma paciente jovem. Analisam a fisiopatologia de hipertensão intracraniana em tumores medulares e a raridade desse tipo de tumor nessa localização, assim como seus aspectos clínico-patológicos. PALAVRAS-CHAVE: hipertensão intracraniana, glioblastoma multiforme espinhal, paciente jovem.

No abstract

No abstract