A 62-year-old woman presented with ischemic pain of her lower limb on 2 occasions, without upper limb or cranial vessel involvement. She was treated with open bypass of her left lower limb when she presented with critical limb ischemia during her second admission. Although bilateral temporal artery biopsies were negative, superficial femoral artery biopsy at the time of surgery confirmed the diagnosis of giant cell arteritis. Corticosteroid therapy was promptly commenced.
Vasculitis refers to inflammation of the systemic vessels. Eosinophilic granulomatosis with polyangiitis (EGPA) is a medium and small vessel vasculitis characterized by hypereosinophilia, pulmonary infiltrates, difficult to treat asthma and polyneuropathies. Diagnosis can often be challenging. In this article, we present a case of a young lady who was diagnosed ANCA negative EGPA.
Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma of chondroblastic origin by EWSR1-NR4A3 rearrangement. Its insidious nature frequently delays diagnosis.
We report an interesting case of a patient presenting with cardiac arrest secondary to hypoxemia who was found to have bilateral pulmonary nodular opacities and idiopathic CD4 lymphopenia.
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