The study was funded by TEC-TOP project (Pays de la Loire region, Angers Loire Métropole, University of Angers, CHU of Angers). None of the institutions had had any role in the collection of data, analyses, and the writing of the manuscript. Larema was supported by Centre Henri Lebesgue, program ANR-11-LABX-0020-0. The CONSTANCES Cohort Study was supported and funded by the Caisse nationale d'assurance maladie (CNAM); it is an "Infrastructure nationale en Biologie et Santé" and benefits from ANR (ANR-11-INBS-0002) grant funding. CONSTANCES is also partly funded by MSD, AstraZeneca, and Lundbeck. Conflicts of interest: None declared. The authors are paid by their institution, and A.D. is also paid as editor of the Archives des Maladies professionnelles et de l'Environnement (Elsevier).