When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthocyanins are a large group of ingredients contained in plants that do not have a nutritional function, but play a significant role in the regulation of metabolic processes in the human body, which has a multidirectional pro-health and preventive effect in relation to many diseases, especially cancer. High hopes in chemoprevention are associated with the biological activity of the most common representative of anthocyanins, i.e. cyanidin-3-glucoside (Cy3G). Most of the studies on Cy3G bioactivity come mainly from in vitro cell line tests and in vivo experimental studies on rodents. Studies of the biological activity of Cy3G most often include: the process of free radical absorption, anti-inflammatory, anticoagulant, insulinotropic, antimicrobial, chemotherapeutic and epigenetic effects. This publication summarizes the results of in vitro studies conducted on various cancer cell lines, which prove the antiproliferative, anti-inflammatory and chemopreventive activity of Cy3G.
Przewód pokarmowy człowieka jest miejscem bytowania wielu drobnoustrojów, przede wszystkim bakterii, ale także wirusów, pierwotniaków i grzybów. Ich liczba przewyższa ilość komórek organizmu człowieka. Mikrobiota jelitowa, czyli wszystkie drobnoustroje zasiedlające przewód pokarmowy, tworzy ekosystem, który w odpowiednim składzie pomaga gospodarzowi utrzymać homeostazę, pełnić różnorodne funkcje fizjologiczne i biochemiczne, uczestnicząc w różnych procesach metabolicznych, a także w regulacji układu odpornościowego. Stan równowagi pomiędzy drobnoustrojami a organizmem nazywany jest eubiozą. Mikrobiota jelitowa pełni istotną rolę w trawieniu, wchłanianiu i metabolizmie składników diety poprzez dostarczanie enzymów, których nie koduje ludzki genom. Enzymy te odpowiadają za rozkład polisacharydów, polifenoli i syntezę witamin [20]. Bakterie wraz z organizmem człowieka tworzą układ obustronnie korzystny,
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