Emulgel is NDDS that is in recent light for its capacity to deliver hydrophobic drugs. In a topical drug delivery system, the most important task is to pass the drug through the barrier and the proper diffusion of the drug in the skin. Emulgel is made up of emulsion and gel where emulsion helps in the delivery of hydrophobic drugs while gel gives proper diffusion, spread ability and improves the stability of an emulsion. It’s a dual release system in which the emulsion is jellified by gelling agents giving us characteristics of both emulsion and gel along with improved patient compliance. In the following review, we will discuss about the emulgel and its types along with its method of preparation, evaluation and applications in a comprehensive way.

Eosinophilic cholecystitis is a rare post-cholecystectomy inflammatory histopathological condition characterized by more than 90% eosinophilic infiltrate in the gallbladder. We present a case of 27-year female presented with abdominal pain, fever, jaundice, altered mental status, shock, leucocytosis, deranged liver function test, and peripheral blood eosinophilia. The patient underwent cholecystectomy and common bile duct exploration. She developed adult respiratory distress syndrome and hospital-acquired pneumonia. From this, we want to emphasize that eosinophilic cholecystitis and cholangiopathy should be a differential diagnosis in patients presenting with allergy, peripheral eosinophilia, obstructive jaundice that are planned to undergo cholecystectomy that will have early critical care intervention.

Malposition of central venous catheter tip inserted into the subclavian and internal jugular vein is a rare unavoidable complication that can be decreased if inserted under ultrasound guidance. We report case series of three patients, two of subclavian and another of internal jugular inserted central venous catheter, in which the catheter malpositioned into ipsilateral internal jugular and subclavian vein respectively but had no effect on patient management. From this, we want to emphasize that the effect of malposition of central venous catheter tip depends upon the indication for which central venous catheter was inserted; it can be detected bedside by ultrasound and flush test.

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