Background: Obesity (Sthaulya) has been one of the primary diseases of the modern period, with its changing lifestyles, climate, and eating habits. Everyone has become a victim of many diseases caused by poor eating habits, and obesity is just one of them. Obesity is the privilege of the new era of robots and materialistic devices. In 2008, the WHO assessed that 1.5 billion individuals, were overweight and more than 200 million men and almost 300 million women were fat. Objectives: To evaluate the effect of Rodhradigana Vasti in Sthaulya. Study Design: This was an open-labelled single-arm interventional clinical study. Methods: 15 patients of Sthaulya were registered from Panchakarma, and Rodhradigana Vasti was administered for 15 days. Statistical Analysis: The data were statistically analyzed using the Wilcoxon Signed Ranks Test for Subjective Parameter and paired t-test for Objective Parameter. Results: In this study, decreased weight, lipid profile and subjective parameters show positive finding after the intervention of Vasti. Conclusion: Rodhradigana Vasti is one of the best remedies for relieving Sthaulya.

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