Neurofunctional approaches play the paramount functions in management of neurological disorders to improve the functional capability after impairments and activity limitations. These interventional approaches aligned with the neuroplasticity theories and all rely on repetition matters to build up engrams for the change of the brain function and activity performance. Affolter approach guides cognitive perceptual interaction through tactile-kinesthetic inputs. Neuromuscular facilitation relays the periphery information to the central nervous system by joint and muscle stimulus by using different techniques such stretching, irradiation, traction and approximation. Neurodevelopmental therapy manages the abnormal movement and postures through hands on facilitation of normal movement and inhibiting abnormal patterns movement. Roods approaches focus on the primitive reflexes through sensory stimuli to the targeted sensory receptors to initiate the appropriate motor pattern development. Brunnstrom approaches build on the synergies to provoke the engagement of the affected limbs. Task-oriented approaches are based on motor learning and involve repeat training with task-oriented activities. It is effective for improvement of the functional performance. It is a training method for encouraging functional movement with an interesting task. And also it improved the dexterity when applied using mixed interventions in hemiplegic.