We report a case of retroperitoneal leiomyosarcoma in a 52-year-old woman, who developed local recurrence, pulmonary, hepatic, peritoneal, pancreatic, subcutaneous and intramuscular metastases two years after surgical resection of the primary tumor. Metastasis to the pancreas, subcutaneous or muscular tissue is very rare; however, presence of a lesion in these locations in a known case of leiomyosarcoma might indicate a metastatic tumor deposit.
A five year old cross bred cow, 24 hours post calving was presented to Teaching Veterinary Clinical Complex (TVCC), Pookode, with the history of recumbency 24 hours post calving. The serum biochemical parameters of calcium, phosphorus and potassium on the first day of presentation were 7.93 mg/dL, 3.82 mg/dL and 3.67 mEq/L, respectively. Tentatively the condition was diagnosed as downer cow with metabolic origin. The cow was treated with calcium borogluconate, flunixine meglumine and inj. Vitamin B1, B6, B12, sodium acid phosphate, vitamin ADE, Selenium, Biotin liquid for 7 days. Along with this, potassium chloride was administered for two days. The supportive treatment was done with lifting of cow using cow sling. Sand bedding was provided along with physiotherapy of rolling of the recumbent cow alternate ways six times a day. The serum biochemical parameters became normal on 8th day and the cow recovered by 13th day.
In India, cervical cancer is the second leading cause of cancer-related mortality among females. Around one-third are expected to develop recurrence or metastasis during follow-up. Liver metastasis is rarely requiring palliative treatment. Patient compliance to strict follow-up is vital to detect early metastasis to be able to improve survival. A 58-year-old lady (International Federation of Gynecology and Obstetrics [FIGO] stage IIIB) was treated with concurrent chemoradiotherapy. During follow-up, she had complained of abdominal pain for which cross-sectional imaging revealed a left lobe liver lesion fistulizing into the stomach. Liver metastasis fistulizing into the stomach is a rarity, and a biopsy is required to confirm metastasis or maybe a second primary. Although palliation in the form of chemotherapy is the standard, minor or major hepatectomy can be considered in patients with good performance status at high-volume centers. A tailored multidisciplinary team approach is required for better survival.
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