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Abstract-We study the deployment of data back-haul nodes for wireless networks with energy constraints. We address the following problem: given the required lifetime of a sensor network, the energy constraint of back-haul nodes, and the area to be covered, what is the minimum number of nodes needed to construct such a back-haul network and what is the corresponding deployment scheme? Finding an efficient deployment scheme involves location management, routing, and power management. We focus on linear networks and formulate a deployment optimization problem. We then propose and analyze a greedy deployment scheme that achieves close to optimal performance. We reveal the closed-form relationship among different design parameters, namely, the number of sensor nodes, the desired lifetime, and the coverage distance. We also study the effect of miscellaneous power consumptions and non-uniform data density, and consider extensions to planar networks.

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Monitoring of anti-malarial drug resistance is vital in Northeast India as this region shares its international border with Southeast Asia. Genetic diversity of Plasmodium parasites regulates transmission dynamics, disease severity and vaccine efficacy. P. falciparum chloroquine resistance transporter (Pfcrt), multidrug resistance-1 (Pfmdr-1) and kelch 13 propeller (PfK-13) genes which govern antimalarial drug resistance and three genetic diversity markers, merozoite surface protein 1 and 2 (Pfmsp-1, Pfmsp-2) and glutamate rich protein (Pfglurp) were evaluated from Tripura, Northeast India using molecular tools. In the Pfcrt gene, 87% isolates showed triple mutations at codons M74I, N75E and K76T. 12.5% isolates in Pfmdr-1 gene showed mutation at N86Y. No polymorphism in PfK-13 propeller was found. Polyclonal infections were observed in 53.85% isolates and more commonly in adults (p = 0.0494). In the Pfmsp-1 locus, the K1 allelic family was predominant (71.2%) followed by the 3D7/IC family (69.2%) in the Pfmsp-2 locus. RII region of Pfglurp exhibited nine alleles with expected heterozygosity of 0.85. The multiplicity of infection for Pfmsp-1, Pfmsp-2 and Pfglurp were 1.56, 1.31 and 1.06 respectively. Overall, the study demonstrated a high level of chloroquine resistance and extensive parasite diversity in the region, necessitating regular surveillance in this population group.

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