In an arbitrary normed space, though the norm not necessarily coming from the inner product space, the notion of orthogonality may be introduced in various ways as suggested by the mathematicians like R.C. James, B.D. Roberts, G. Birkhoff and S.O. Carlsson. We aim to explore the application of orthogonality in normed linear spaces in the best approximation. Hence it has already been proved that Birkhoff orthogonality implies best approximation and best approximation implies Birkhoff orthogonality. Additionally, it has been proved that in the case of ε -orthogonality, ε -best approximation implies ε -orthogonality and vice-versa. In this article we established relation between Pythagorean orthogonality and best approximation as well as isosceles orthogonality and ε -best approximation in normed space.