This was a prospective non comparative study conducted at Mahatme Eye Bank Eye Hospital, Nagpur, India. 175 eyes with Pseudo-exfoliation syndrome (PXF) undergoing cataract surgery by phacoemulsification were studied. The study aimed at finding out impact of age, gender, pre-operative Intra Ocular Pressure (IOP) and Anterior Chamber Depth (ACD) on the intraoperative complications of phacoemulsification surgery in these patients. It was found that association of age, gender and intraoperative complications was not significant (P value -0.0958). No significant impact of preoperative intraocular pressure and intraoperative complications was noted. The mean anterior chamber depth in complicated cases was 2.42 +/-0.37 as compared to 2.72 +/-0.43 in eyes without complications. The relation between these groups was statistically significant (P value = 0.031).