Background: Non-alcoholic fatty pancreas disease (NAFPD) is an emerging clinical entity. NAFPD is characterised by excessive fat deposition in the pancreas in the absence of alcohol consumption. Recent studies suggest that NAFPD might be associated with beta cell dysfunction, insulin resistance and inflammation which might lead to development of diabetes. NAFPD might be used as an initial indicator of glucometabolic disturbances and identify the patients with prediabetes.Methods: This was a cross sectional study in which the glycemic status of 50 patients with NAFPD with ultrasonographic evidence of increased echogenicity of pancreas was assessed and association between glycemic variability and NAFPD was determined. The patients were also assessed for the ultrasonographic evidence of fatty liver.Results: Pre-diabetes was noted in 32% subjects while diabetes was noted in 20% subjects. Thus, 52% patients with NAFPD had abnormal glycemic status. The 48% subjects i.e., 24 patients had normoglycemia. The presence of fatty liver was statistically significant in normoglycemia and diabetes mellitus with p=0.001 and 0.045 respectively. No statistically significant association was noted between fatty liver and prediabetes with p=0.175. No causal relationship was seen between fatty liver and glycemic variability in patients with NAFPD.Conclusions: NAFPD is associated with impaired glycemic status. It is also seen frequently with fatty liver. Its early detection may help to identify the patients with prediabetes who may benefit from timely introduction of interventions to reduce the rising morbidity and mortality due to diabetes mellitus.
Systemic lupus erythematosus is a multisystem autoimmune disorder and its complications include cerebral vasculitis and vasculopathy which can be the first manifestation of SLE. Subarachnoid haemorrhage due to rapid aneurysm growth and rupture is a major neurosurgical emergency associated with significant morbidity and mortality. There is need for more rapid diagnosis and aggressive treatment of SLE patients with unruptured aneurysms. Authors report a case of 23 years old female, a newly diagnosed case of SLE complicated by rupture of cerebral aneurysms.
Diabetic mastopathy is used to describe the breast related complications of diabetes mellitus. It is a benign breast disease. Its accurate diagnosis in appropriate clinical and radiological setting shall avoid unnecessary surgical excision. Authors report a case of 25 years old female, a known case of Type 1 diabetes mellitus who presented with a rare finding of diabetic mastopathy.
AIM : The study aimed to nd the link between the fat deposition in pancreas and liver and metabolic syndrome. METHODOLOGY : It was a cross sectional study . 50 patients with ultrasonographic evidence of fatty pancreas were included and were evaluated for the presence of fatty liver on ultrasonography and were assessed for the presence of metabolic syndrome. RESULTS: Metabolic syndrome was detected in 62% of patients of Non alcoholic fatty pancreas disease (NAFPD). The overall prevalence of fatty liver was 72% in patients with NAFPD. The presence of fatty liver in the studied patients increased the number of parameters of metabolic syndrome. It was statistically signicant (p=0.043). CONCLUSION: NAFPD is closely related to metabolic syndrome and fatty liver
Systemic lupus erythematosus (SLE) is a multisystem disorder of autoimmune etiology. Renal involvement is frequently seen in SLE. Tubular dysfunction is also seen in SLE. Authors report a case of distal renal tubular acidosis in patient with SLE.
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