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as AbstractAt least six separate rare earth and uranium-bearing daughter crystals occur in fluid inclusions hosted by andraditic garnet from the Mary Kathleen REE-U ore skarn, Queensland, Australia. The daughter minerals are particularly high in La, Nd and Ce which reflects the relatively high concentration of these in the bulk ore (La20 a = 33.5%, Nd20 3 = 9.1% and Ce20 2 = 51.5% of the 2.6 wt. % REE common in the ore). The host garnets themselves contain up to 7600 ppm REE and 5 to 2700 ppm U. The energy-dispersive spectra (EDS) are consistent with the following minerals: a (Y, Ce, U, Ca, Fe, Nb, Ta) mineral; a (Ca, Fe, Ce) carbonate(?) mineral; a (Fe, Ca, Y, Ce, Nb, Ta) mineral; a possible carbonate of La, Mn and Nd; a chlorite of Mn and La as well as a possible chloride or oxychloride of K, Mg, Mn and La. Their occurrence infers that relatively high concentrations of REE and U prevailed in the original, oxidized, concentrated (30-70 wt. % total dissolved salts), high-temperature (550-670 ~ ore solutions. Their presence as daughter crystals may be due to the fact that CaC12 is a dominant salt in the solutions and that the latter's solubility was sufficiently high to 'salt out' the less soluble REE-U components.

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Taxane‐induced pneumotoxicity is rare. However, 1–5% of patients taking docetaxel may develop severe pneumotoxicity. This has been limited to case reports in the literature. We report seven breast cancer patients who developed docetaxel‐induced diffuse parenchymal lung disease (DPLD) of an organizing pneumonia pattern on high‐resolution computed tomography (HRCT). The patients presented with progressive breathlessness within four weeks of the final dose. All had an organizing pneumonia pattern on their HRCTs, without other evidence of infection. Restrictive lung disease with low carbon monoxide diffusing capacity (DLCO) was noted, with desaturation on a 6‐min walk test (6MWT). They were started on prednisolone. Repeated HRCT after four to eight weeks from the commencement of steroid treatment showed marked improvement. The clinical and functional improvement were also significant. One patient succumbed to the illness as a result of severe lung involvement. Docetaxel‐induced DPLD is a fatal adverse effect, which can be managed by the cessation of the drug and starting on steroids in adequate doses.

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