: Retroperitoneal masses constitute a heterogeneous group of uncommon lesions and represent a challenge due to overlapping imaging findings. Most are malignant lesions. To evaluate the role of CT in the detection, localization and characterization of retroperitoneal masses and to compare and correlate with post-surgical evaluation and histological evaluation whenever possible.: The cross-sectional study carried out in the Department of Radiodiagnosis for a period of 2 years. Present study involved 50 patients of either sex belonging to various age groups. The CT scan findings were correlated with the findings at surgery and histopathological examination. : Renal masses were the most common retroperitoneal mass(48%). Renal cell carcinoma was the most common renal tumour (66.6%)and pancreatic adenocarcinoma was the most common pancreatic tumour (68.7%). Majority of cases of retroperitoneal mass were in the age group 51-70 years. Males were affected more than females in a ratio of 1.94: 1. Mass in the abdomen was the most common clinical presenting feature (40%). CT accuracy in the diagnosis of retroperitoneal tumours was 96%. CT is an essential diagnostic modality in diagnosing and characterizing retroperitoneal masses. It establishes the location of such masses and shows in great detail the associated findings.
Objectives- This study was undertaken to evaluate the effect of Ethanolic extract of Triticum aestivum (TAE) on different anxiety like behaviour induced by Chronic unpredictable stress in wistar albino rats. Materials and methods- Effect of TAE was studied on chronic unpredictable stress induced rats. The reference standard drug (Diazepam 1mg/kg po) and the test drug, TAE at doses of 150mg/kg and 200mg/kg b.w. were given to rats for 14 days. Anti-anxiety activity was assessed by using Light and Dark Box test. Then the locomotor activity of rats was assessed as indicator of anxiety. Animals were sacrificed at the end of this experiment..The adrenal and spleen weight, ulcer index as well as various biochemical parameters like Malondialdehyde (MDA) and Superoxide dismutase (SOD) were assessed. Results- The stay in Light box was increased, rearing activity was increased to a significant level in both Diazepam and TAE-200 mg/kg treated rats and this effect was comparable to that of normal non-stressed vehicle treated rats. Chronic stress caused elevation of MDA and depression of SOD level which is reversed by Ethanolic extract of Triticum aestivum (TAE).
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