Duplex stainless steel (DSS)-2205 comes under hard-to-machine material owing to its inherent properties but more applications in severe working conditions. Hence, investigating the effect of cutting fluids and machining parameters is essential. In the present work, an attempt has been made with Minimum Quantity Lubrication (MQL) the investigate the performance of Deionized (DI) water, neat cut oil, and emulsified fluid on Cutting Force (CF) during turning of Duplex Stainless Steel (DSS-2205). The experiments were conducted based on face central composite design (CCF) in response surface methodology, varying speed, feed, and depth of cut in three levels. The Analysis of Variance (ANOVA) is to identify significant factors that influence the response. The results revealed that using emulsified fluid's cutting force gives better results than the DI water and neat cut oil. Feed rate is the most significant factor for emulsified fluid contribution was 53.61% for neat cut oil 48.89% and DI water 26.11%. It also reveals that the contribution of the depth of cut is slightly lesser than the feed rate. However, the contributions of cutting speed in all three Deionized (DI) water, neat cut oil, and emulsified fluid working fluids are negligible.