A manual of Homoeotherapeutics, An introduction to the study and practice of Homoeopathy is a book which is not available presently. This book contains therapetic indications as well as the pathogenesis of the drugs which is much useful for today's practitioners. This book is published for not only the homoeopathic practitioners but to the physicians of old school those who wish to know the therapeutics.

Objectives:Hypothyroidism is a disease in which the thyroid gland does not produce enough thyroid hormone.It is the second most common endocrine disorder among women.Common causes are autoimmune disease such as Hashimoto’s thyroiditis, surgical removal of the thyroid and radiation therapy.Symptoms of Hypothyroidism include weight gain, alteration in cognition, fatigue, infertility and menstrual abnormalities.Thyroid stimulating hormone is highly sensitive to thyroid dysfunction and is used to evaluate thyroid disorders.Monotherapy with Levothyroxine is the standard for treating hypothyroidism in the conventional method.Apart from coventional method of treatment homoeopathy also has a scope in the treatment of hypothyroidism. Methods: This is a series of three cases which presented with symptoms of Hypothyroidism thoroughly evaluated and treated with constitutional homoeopathic medicine in a variable period of time.Assesment of thyroid stimulating hormone was done to see the improvement in the cases . Results: A marked improvement in the clinical symptoms as well as the pathological report was observed. Conclusion: This case series shows that Homoeopathic intervention can be used in the treatment of Hypothyroidism.

Abstract:Introduction:Pregnancy Induced Hypertension (PIH) results from imbalance between pro-angiogenic factors (VEGF & PIGF) and antiangiogenic factors (sVEGFR-1/sflt-1).Subjects and methodology: A mixed random study comprising of random cases of different gestational ages 28-36 wks of PIH mothers along with control cases till completion of pregnancy after delivery. Age of enrolled mothers and their gestational age, blood pressure, serum free VEGF and sVEGFR-1(sflt1) were compared in both groups (control n=36, PIH n=36). Blood pressure of both control and PIH mothers just before and after delivery showed significant correlation (p<0.0001). Serum levels of free VEGF were lower among PIH mothers at 28-36 wks (p <0.0001) and just before delivery (JBD) (p <0.0001) than normal control antenatal mothers and more or less similar in both groups at just after delivery (p <0.390). Serum sflt1 level (6459.81 ±1811.07 pg/ml) of PIH mothers showed higher value than control mothers (1062.19 ± 165.98 pg/ml) at the time of presentation and also just before delivery(JBD) & after delivery(JAD) and was highly significant ( p < 0.0001). Serum free VEGF level of PIH mothers was negatively correlated with systolic r= -0.247, p = 0.147) and diastolic (r =-0.220, p =0.197) blood pressure. The increased serum sflt1 level of PIH mothers was positively correlated with systolic (r = 0.299, p = 0.07) and diastolic (r = 0.309, p = 0.067) blood pressure. Semi quantitative expression of VEGF R1 and PCNA LI of placenta showed increased (3+) expression of VEGF R1 of 13 (43.33%) and > 50% PCNA LI expression of 12 (40%) cases than control. Discussion &Conclusion:The elevated levels of systolic and diastolic blood pressure along with alteration of proangiogenic and angiogenic growth factors among PIH mothers than normotensive control may help to identify PIH mothers as early as possible and referring them to higher/tertiary centers for better management and prevention of its grave complications of PIH.