Obesity and its concomitant health risks are among the most common conditions managed by health care practitioners. The limited long-term effectiveness of conventional weight management has led to researching alternative medicine and one which is widely accepted is the herbal products by virtue of its safety in long term use. The study was conducted to evaluate effect of caplet of Garcinia extract with reference to reduction in BMI and skin fold thickness in obese individuals. This study was performed according to a double-blind, randomized, placebo-controlled, design. Subjects aged 18 to 60 years with Obesity as decided by BMI > 25 Kg/m 2 to 35 Kg/m 2 falling in the category of overweight and class I obesity were included in the study. A total of 110 individuals participated in the study. Subjects were randomly assigned into two groups of 55 each to receive treatment for 4 months with Garcinia or matching placebo at a dose of 1 caplet twice daily. All the subjects completed the study as stipulated. At the end of 4 months, Garcinia group had significant reduction in BMI and skin fold thickness when compared to the placebo group and baseline values respectively. No severe adverse effect was observed at any time in the study period. Compliance to treatment was good. It is therefore expected that Garcinia may be useful for the prevention and reduction of obesity.
Objective: Labor induction by medication is now preferred by many obstetricians. The impact of induction remains ambiguous, although many studies and systematic reviews have been conducted. Few studies have reported for its better outcomes while other studies with poor outcomes. The objective of the study is to identify the common indications of induction and the risk of cesarean section after induction.
Methods:Various standardized databases, such as Pub Med, Scopus, and Google Scholar, were used to collect the scientific studies, where prostaglandin was used as drug of choice for induction of labor. The key words used were induction of labor, indications of induction, induction by misoprostol, induction and risk of cesarean section, etc. The survey spans over 22 years of study articles published from the year 1995-2017.Result: A total of 112 studies have been included to analyze the indications and risk of cesarean section. The most common indication found in most of the studies was post-term pregnancy. The risk of cesarean section varied from 3% to 48.7%. The common reasons for which the cesarean section was planned were, failed induction, nonprogress of labor, fetal distress, and undiagnosed CPD.
Conclusion:Most of the studies recommend induction of labor as a safer option with lower risk of c-section.
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