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An unknown impurity in the fermentation-based drug substance lovastatin at 0.52 RRT was observed invariably in all batches when analyzed by HPLC as per the PhEur monograph. This impurity was isolated from the impurity-enriched sample using reversed-phase preparative HPLC and characterized by using spectroscopic (PMR, CMR, MASS, and UV) techniques as the structurally-related compound Monacolin-X, having the molecular formula C24H34O6 and the chemical name 2-methyl-3-oxobutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester.

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Methanolic extracts of 4 Indian medicinal plants, traditionally used in different ailments, were evaluated for antioxidant activity using DPPH (1,1-diphenyl-2-picryl hydrazyl) radical scavenging assay. Among the extracts, C. lanceolatus significantly decreased the absorption at 10 µg/ml indicating that it is effective even at a very low concentration.