Introduction:Traditional wound closure techniques include skin sutures and metal clips. The ideal incision closure should be simple, effective, safe, rapid, inexpensive, painless, cosmetic, and bactericidal. Cyanoacrylate glue has good neovascularization, epithelialization,and fasterApplication.Soit can be considered an alternative for skin closures. Methods:A study was conducted on 50 individuals undergoing elective surgery in the department of general surgery. They were randomized into 2 groups. In group A skin closure was done with skin glue and in group B skin closure was done with sutures. Post-op pain was assessed with VAS and cosmesis was assessed with a modified Hollander cosmesis scale. The time taken for closure was assessed using a stopwatch. Results:Skin closure with skin glue was quicker than traditional closure. The average time for skin closure with glue was 1 minute and 14 seconds while it was 3 minutes and 47 seconds in the suture group. The postoperative pain was comparatively less in people who had closure with glue. Cosmesis was better in patients who had closure with glue compared to sutures.The overall satisfaction level was better in people who had closure with glue compared to those who had closure with sutures. Conclusion:According to this study, using skin glue for skin closure in clean surgery reduces thewound closure time with a superior cosmetic effect. The usage of skin glue can greatly save healthcare expenses and is favored by patients due to the simplicity of postoperative wound care. The study established the efficacy and advantages of this unique technique.The broad adoption of this innovative approach may drastically reduce the need for sutures in clean surgery.