The revolutionary development of green technology, such as ultrasound-assisted extraction, has had a significant impact on the extraction methods of natural compounds with pharmacological potential. These methods are considered green because they are environmentally friendly, minimizing the use of toxic solvents, energy consumption, and CO2 generation. Antimicrobial resistance is a global public health problem. Pathogens of dermatological and nosocomial relevance are more frequent because they are resistant to antimicrobials. Agave nuusaviorum leaves are used in traditional medicine to treat onychomycosis and inflammatory processes. Here, the antimicrobial activity of hydroethanolic extract of A. nuusaviorum leaves obtained by ultrasound-assisted extraction was evaluated. The antimicrobial activity was tested against 14 pathogens with dermatological and nosocomial relevance by the agar diffusion technique. The extract exhibited an antimicrobial effect on all microorganisms tested, showing inhibition zones of 9–16 mm for Staphylococcus aureus, Candida albicans, Candida parapsilosis, and eleven isolates of Trichophyton. The extract’s minimum inhibitory concentration ranged between 0.5 mg/mL for Staphylococcus aureus, 0.25–1 mg/mL for yeast, and 0.4–1.25 mg/mL for molds. The phytochemical screening revealed the presence of terpenes, phenolic acids, tannins, carbohydrates, and steroids in the extract. The results showed that A. nuusaviorum leaves have broad-spectrum antimicrobial potential.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.