Objective: To determine the incidence of HELLP syndrome amongst cases of Eclampsia and severe pre-eclampsia admitted to our hospital and to study the correlation of laboratory parameters with the mean arterial pressure (MAP) and with each other. Method: 238 cases of severe pre-eclampsia and eclampsia were studied for their clinical features, laboratory parameters and outcome. Cases were divided into two groups: non HELLP and complete HELLP for comparison of the maternal and perinatal outcome. The levels of Alanine Transaminase (ALT) were compared against other laboratory parameters for correlation. The mean arterial pressures (MAP) of the patients were computed to investigate whether its levels had any correlation with the derangement of ALT. Statistical analysis was done in SPSS software and spearman's correlation was run for the laboratory parameters. Results: No significant difference was seen in the maternal and perinatal mortality in the two groups. ALT showed no correlation with MAP as with LDH, platelets and hemoglobin and a weak but significant correlation with the parameters of renal function. Conclusion: Our population shows a low incidence of HELLP syndrome; the hepatic dysfunction correlates with the renal dysfunction without any correlation with the MAP.

Association of serum lipid profile with gestational proteinuric hypertension is highly suggested to reflect some new diagnostic tools. Simple measurement of serum lipid parameters may be of good predictive value in toxaemia of pregnancy, avoiding the costly endocrinal investigations. The objectives of present study is to study serum lipids in pregnancy induced hypertension and to determine if there is any change in lipid profiles in subject of preeclampsia as compared to normal antenatal female. The study was carried out on pregnant women and non-pregnant women attending or admitted in obstetrics and gynaecology department of NSCB Medical college and hospital, Jabalpur between 1 st june 2012 to 31 st October 2013. Each serum sample from two groups was evaluated for total cholesterol, Triglyceride, HDL-Cholestrol, LDL-Cholesterol and VLDL-Cholesterol. Comparison is drawn and analysed using chi-square or fisher's exact statistic as appropriate. Dyslipidemia is found in the form of significantly increased total cholesterol, LDL, VLDL & Triglyceride concentration in patients of preeclampsia as compare to normotensive pregnant women. Dyslipidemia play an important role in pathophysiology of preeclampsia. The prevention and correction of various causative factors for dyslipidemia may significantly prevent development of preeclamsia.

A case of primary ovarian twin pregnancy is presented. A 30-year-old woman, gravida 3 para 2, was admitted to Medical College Hospital, Jabalpur, for postdated pregnancy with intrauterine fetal demise. Ultrasonography showed a break in the continuity of the uterus suggestive of a ruptured uterus. On laparotomy, twin ovarian pregnancy was discovered. One fetus was postdated, showing signs of maceration. The bones of the other fetus were discovered in the sac, suggestive of an autolysed fetus of approximately 26 to 28 weeks of gestation.

Background: Present study was designed to note the indications for and the complications and outcome of women on mechanical ventilation in our obstetric intensive care unit, and in addition to look for the applicability and correlation of Sequential Organ Failure Assessment (SOFA) scores for the prediction of outcome in these women.Methods: A prospective observational study was conducted in the obstetric intensive care unit of our teaching hospital which included all women requiring mechanical ventilation in the study period. The diagnosis of the woman on admission, the clinical course and outcome along with total maximum sequential organ failure assessment (SOFA) score and SOFA score for each system were noted. Women were divided into two groups, survivors and non-survivors. Student t test and chi square test were used for analysis.Results: The foremost indication for mechanical ventilation was hypertension in pregnancy namely eclampsia and pre-eclampsia, followed by obstetric hemorrhage and then by hepatic failure. Maternal mortality rose significantly as the number of days of mechanical ventilation increased (p value <0.05). The total SOFA score correlated highly significantly with the outcome (p<0.0001).Conclusions: In women with eclampsia and pre-eclampsia suffering from respiratory failure, survival is inversely correlated with the number of days of mechanical ventilation. The total SOFA score is highly predictive of the woman’s outcome and all individual organ system scores also significantly correlate with outcome except for the score of coagulation system.

Peripartum cardiomyopathy is a rare complication in pregnancy but is more commonly found in the patients of preeclampsia and eclampsia. The purpose of study is to evaluate incidence of peripartum cardiomyopathy among cases of preeclampsia and eclampsia. This is a prospective observational study. A total of 190 cases of preeclampsia and eclampsia were studied for features of PPCM and subjected to echocardiography. Out of 190 subjects, 3.7% had ndings suggestive of PPCM. Incidence of PPCM was 0.009 per year among cases of pre-eclampsia and eclampsia and the incidence of PPCM among 6028 deliveries was 0.001 per year.