IntroductionFabric quality alone does not fulfil all the criteria for production of high quality garments. The conversion of a two-dimensional fabric into a three-dimensional garment involves many other interactions[1] such as selection of a suitable sewing thread, optimization of sewing parameters, ease of conversion of fabric to garment and actual performance of a sewn fabric during wear of the garment.The selection of sewing thread for a fabric depends on the dimensional and mechanical properties of the fabric and the sewing thread, their compatibility, the sewing process and the end use of the garment [2][3][4][5][6][7][8][9][10][11]. Similarly the quality and performance of a sewn garment depends on various factors such as seam strength, slippage, puckering, appearance and yarn severance [4,12]. All these factors combined together contribute to sewability of the fabric which is considered to be one of the most important aspects of clothing science.The study of sewability in clothing manufacture in general and its importance, particularly in denim based clothing, has considerable relevance in today's advanced garment manufacturing processes. Modern garment manufacturing processes use motorized high-speed sewing machines, which exert very high tensions in the thread and also high forces of penetration of needles in the fabric [10,13]. As a result, both the sewing thread and the yarns in the fabric get abraded/severed during the seaming process. The extent of damage becomes more critical if the fabric being used is of a dense, thick and heavy construction such as denim. At the same time, if the sewing thread is not properly selected with respect to the construction of the fabric and nature of treatment the thread will get during sewing, the seam performance will deteriorate in the final garment. In the context of denim based garments, particularly trousers and jackets, sewing thread is not only used for joining the fabric but also for decorative purposes along the seam line. The thread poses a linear projection on the surface of the garments and is subjected to more abrasion than the garment. Therefore, unless the sewing thread chosen for a denim garment is stronger, it may break before the fabric does.This study evaluated the sewability of denim in relation to the dimensional and mechanical properties of the fabric and sewing threads.

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Background: Medicinal uses of natural phenolic acids and its synthetic derivatives have been augmented in recent years. Phenolic acids are chemically defined secondary plant metabolitesand being moieties or leads are much versatile in nature with a widescope of biological activities which seek the attention of researchers across the worldto synthesize different derivatives of phenolic acids and screen them for their various biological properties.These compounds are of meticulous interest due to the properties they possess and their occurrence.Based on the convincing evidences reported in the literature, it is suggested that phenolic acids andtheir derivatives are promising molecules as a drug. Objective: The present review article aims to bring together the information on the biosynthesis, metabolism, and sources of phenolic acids and emphasize on the therapeutic potential of phenolic acid and its synthetic derivatives to comprehensively portray the current scenery for researchers interested in designing drugs for furthering this study. Conclusion: Phenolic acids being moieties or lead are much versatile in nature as they possess a wide range of biological activities like antimicrobial, antioxidant, antiviral, antiulcer, anti-inflammatory, antidiabetic, anticancer and many more which offers researchers to explore more about these or many untapped benefits in medicinal field. The information mentioned in this article will be helpful to the forthcoming researchers working in this area. Phenolic acids have massive potential to be investigated for novel medicinal possibilities and for the development of new chemical moieties to treat different diseases of clinical importance.