High incidence of antibiotics resistant bacteria spurred researchers to obtain alternative antibacterial compounds. One source of potential antibacterial compounds i.e plants. Bougainvillea (Bougenvillea glabra) has been believed by the people of Indonesia to have medicinal properties, but its potential as an antibacterial has never been studied in Indonesia. The aims of this study were to determine the bioactive compounds ethanol extract of leaves and flowers of B. glabra as well as the minimum concentration of extract capable of inhibiting and killing bacteria growth.Minimum Inhibition Concentration (MIC) was done used microdilution method and Minimum Bactericidal Concentration (MBC) agar plate method. Ethanol extract of leaves and flowers of B. glabra possess antibacterial activity against pathogenic bacteria; Bacillus sp., S. aureus, Salmonella sp., E. coli, P. aeruginosa and K. pneumoniae. Salmonella, Bacillus sp., and S. aureus growth is most vulnerable (p<0.05). The antibacterial activity of leaf and flower extracts was not significantly different (p>0.05) against all test bacteria. Antibacterial potency of leaves and flowers B. glabra suspected of flavonoids, tannins, terpenoids and alkaloids. POTENSI ANTIBAKTERI DAUN DAN BUNGA BUGENVIL (Bougenvilea glabra)ABSTRAK Angka kejadian bakteri resisten antibiotik yang tinggi memacu peneliti untuk memperoleh senyawa antibakteri alternatif.Salah satu sumber senyawa antibakteri yang berpotensi yakni tumbuhan.Tanaman bugenvil (Bougenvillea glabra)merupakan salah satu jenis tumbuhan yang diyakini oleh masyarakat Indonesia memiliki khasiat obat, namun potensinya sebagai antibakteri belum pernah diteliti di Indonesia.Penelitian dilakukan untuk mengetahui kandungan senyawa bioaktif ekstrak etanol daun dan bunga B. glabra serta konsentrasi minimum ekstrak yang mampu menghambat dan membunuh pertumbuhan bakteri.Konsentrasi Hambat Minimum (KHM) menggunakan metode mikrodilusi dan Konsentrasi Bakterisidal Minimum (KBM) menggunakan metode cawan agar. Ekstrak etanol daun dan bunga B. glabra memiliki aktivitas antibakteri terhadap seluruh bakteri uji; Bacillus sp., S. aureus, Salmonella sp., E. coli.,P. aeruginosa, dan K. pneumoniae. Menariknya pertumbuhan P. aeruginosaresistenklorampenikol, ternyata rentan terhadap ekstrak etanol daun dan bunga B. glabra.Bakteri Salmonella, Bacillus sp., dan S. aureus pertumbuhannya paling rentan terhadap ekstrak etanol daun dan bunga B. glabra (p<0.05).Daya antibakteri ekstrak daun dan bunga berbeda tidak nyata (p>0.05) terhadap seluruh bakteri uji.Potensi antibakteri daun dan bunga bugenvil diduga dari kandungan flavonoid, tanin, terpenoid, dan alkaloid. Kata kunci: antibakteri, bugenvil, ekstrak etanol SANITAS: JURNAL TEKNOLOGI DAN SENI KESEHATAN

Solid bath soap is a cosmetic preparation to remove dirt from skin surfaces. Kaffir lime peel is a good natural ingredient for skin health. The aim of this study was to produce cosmetic preparation of solid bath soap from a thick extract kaffir lime peel with several concentrations. The thick extract of kaffir lime peel is made by maceration by dissolving 500 grams of powder with 96 % ethanol as solvent as much as 1,000 mL for 2x24 hours and concentrated using a rotary evaporator at 500 C. the method used in soap making is cold processing. The result of the study was a solid bath soap, smelling of fresh orange, bluish color to turquoise blue depends on the concentration of the active substance of kaffir lime extract, soft texture and homogeneous color, Formula 1 with concentration of kaffir lime peel extract of 1 % has pH 10.0, foam height of 5.0 cm, water content was 1.76% and free fatty acids was 2.51%. Formula 2 with concentration was kaffir lime peel extract of 3 % value pH 10.0, foam height of 5.0 Cm, moisture content of 1.95 % and free fatty acids was 2.51 % while formula 3 with an extract of 5 % has a pH 10.0 foam height was 5.0 cm, water content was 0.73 % and free fatty acid was 2.51 %. Solid bath soap with thick extract off kaffir lime peel meets the requirements of SNI number 3532 of 2016 for pH, and moisture content tests while the free fatty acid test does not meet these requirements of SNI

Pytiriasiscapitis or dandruff is a condition of exofoliate peeling of the stratum corneum layer in the scalp. There are some factors that suspected to caused dandruff such as increased production of sebum, sensitivity individual against the sebum and microbiota activity in scalp, i.eMalasseziafurfur, Malassezia globosa, Pytirosporumovale, and Candida albicans. Therefore, treatment of dandruff is aimed to reduced sebum on the scalp and inhibit the growth of yeast population that causes dandruff. The juice of kaffir lime fruit (Citrus hystrix DC.) has been used by Indonesian people for tradisional therapy of dandruff. This study thas been conducted to find out antidandruff activities of M. furfur from kaffir lime fruit juice, peel, and leaves of kaffir lime tree extracted by ethanol, ethyl acetat, and n-hexan solvents. Antifungal activitiesis measured by inhibition zones using well diffusion agar methods.All citrus extracts showed antifungal activities against M. furfur with ethyl acetat solvent indicated the highest antidandruff activities, then followed by n-hexan, and ethanolicsolvent; although ethyl acetat and n-hexan was not significantly different (p>0.05).Leaves extract showed highest inhibition activities, then followed by fruit juice and peel extract, although leaves and fruit juice extracts was not significantly different (p>0.05).Part of the plant citrus consist of a alkaloid, saponin, tannin, phenolic, flavonoid, terpenoid, glikosida, and steroid. Antifungal activities suspected of phenolic, flavonoid, and terpenoid compounds. These results suggested that kaffir lime are effective against dandruff microbial and has potential as a herbal shampoo for dandruff treatment. AKTIVITAS ANTIKETOMBE EKSTRAK JERUK PURUTMENGGUNAKAN BEBERAPA JENIS PELARUT ABSTRAK Pytiriasiscapitisatau lebih dikenal sebagai ketombe, merupakan suatu kondisi eksfoliasi atau pengupasan berlebih pada lapisan stratum korneum di kulit kepala.Beberapa faktor yang diduga memacu timbulnya ketombe, antara lain: peningkatan produksi sebum, sensitivitas individu terhadap sebum dan aktivitas mikrobiota kulit kepala, sepertiMalassezia furfur, M. globosa.,Pytirosporumovale dan Candida albicans.Karena itu, pengobatan ketombe ditujukan untuk mengurangi sebum pada kulit kepala dan menghambat pertumbuhan populasi khamir penyebab ketombe.Air perasan buah jeruk purut (Citrus hystrixDC.) telah digunakan secara tradisional untuk mengatasi ketombe. Telah dilakukan penelitian untuk mengetahui aktivitas antifungi penyebab ketombe M. furfurmenggunakan metode difusi agar terhadap ekstrak air perasan buah, kulit buah dan daun jeruk purut dengan pelarut etanol, etil asetat, dan n-heksan.Seluruh ekstrak; ekstrak etanol, etil asetat, dan n-heksan dari air perasan buah, kulit buah, dan daun jeruk purut memiliki aktivitas penghambatan terhadap jamur penyebab ketombe M. furfur.Seluruh ekstrak jeruk purut mampu menghambat pertumbuhan M. furfur.Ekstrak etil asetat memberikan aktivitas penghambatan tertinggi, kemudian ekstrak n-heksan dan etanol; walaupun penghambatan ol...

Antibiotic-resistant pathogenic bacteria contamination has been found in chicken meat products. Chicken meat is obtained from a local market in South Jakarta, Indonesia. Identification of bacteria in was done using conventional methods with selective media and biochemical tests. Furthermore were carried out using vitek2 compact to confirmation identification and pattern of antibiotic resistance. The results obtained 1 isolate Enterococcus faecalis, 1 isolate Proteus mirabilis and 3 isolates Escherichia coli. 1 isolate E. Coli was resistant to the antibiotics ampicillin, sulbactam, ciprofloxacin and trime-thoprim/sulfamethoxazole. P. mirabilis was resistant to tigecycline and nitrofurantoin, while E. faecalis was resistant to erythromycin, quinupristin/dalfopristin, and tetracycline. Based on the results of the study, it is very important to choose a seller who is clean and always cooks chicken meat until it is cooked to inhibit the growth of bacteria.

Honey is a highly nutritious food product and consumed by almost all the population in the world. It has a function as an antimicrobial. Staphylococcus aureus (S. aureus) is a common Gram-positive bacteria in food and Escherichia coli (E. coli) is a Gram-negative bacteria that often appears in environmental sanitation issues that both can cause infectious diseases.  Some infectious diseases can be treated with antimicrobials such as honey. The purpose of this study was to test the antimicrobial effects on honey products distributed in Pasar Minggu area. The antimicrobial effect test was performed in vitro using agar diffusion method by measuring the inhibition zone formed where the bacteria growth was inhibited by the presence of sample. The concentration of samples were 25%, 50%, 75%, and 100% (not diluted) and as aquades control. The results showed that honey tested with various dilution concentrations resulted inhibition zone and. The higher concentration of the inhibited zone zone showed antimicrobial activity against S. aureus and E. coli.