The achievement of learning objective of Biology, especially Phanerogamic Botany requires several important aspects, namely conceptual understanding and metacognitive skill. Analysis of conceptual understanding of Botany and metacognitive skill is needed to know to what extent are both aspects of achieving the learning objectives. The research aims to know and analyze the conceptual understanding and metacognitive skill of college students to achieve course objectives. The research is conducted in July 2018 at the Universitas Negeri Jakarta in Phanerogamic Botany course Eudicot sub-course material with 77 students as sample. The research includes quantitative research with descriptive approach. Results obtained are, among others, the mean of conceptual understanding of Botany and metacognitive skill is 63.07 and 50.15, respectively, which is low based on the achievement score. The analysis result indicates that conceptual understanding of Botany is considered as low due to the difficulty faced by students in finding an example for each clade and in understanding the scientific terms that are the base of the learning. Students, however, can apply the concept into problems faced and students' metacognitive skill in student planning aspect is unable to arrange goals to be achieved to prioritize the learning.

The use of question instrument in determining achievement of students' study goal can be referred from the score achieved by the students in solving contextual questions with solution or solving strategy in high level of thinking. The research aims to get integrated assessment tools of conceptual understanding of Pteridophyta and metacognitive skill that is validated and can be used in learning activity. The research is conducted in July 2018-November 2019 at Universitas Negeri Jakarta, course of Botany Cryptogamae, sub-course Pteridophytes. This is a Research and Development study using 4D method (Define, Design, Develop, and Disseminate). However, the research will be conducted up to the develop phase only. The result shows that integrated assessment tool on conceptual understanding of Pteridophytes and students' metacognitive skill is proper to be used, with expert validation result shows 78.13 on criteria for concept understanding, and 79.17 for students' metacognitive skill. Result of instrument validation shows more than 0.396, means it is valid, and reliability more than 0.6.

Pengetahuan gizi merupakan landasan perilaku gizi seseorang, yang akan berefek pada asupan makanan dan status gizi siswi. Tujuan penelitian ialah mengetahui hubungan pengetahuan gizi dan asupan makanan dengan status gizi. Jenis penelitian adalah deskriptif dengan desain cross sectional. Subjek penelitian ini sebanyak  51 siswi Mts Darul Ulum kelas 8 dan 9. Penelitian dilakukan bulan September 2019-Februari  2020. Uji hubungan menggunakan uji  Pearson dan uji Sperman’s rho. Uji korelasi pengetahuan gizi dan asupan energi p=0,103;  protein p=0,556; lemak p= 0,570; karbohidrat p=0,261; vitamin A p=0,036; vitamin D p=0,745; vitamin E=0,506; vitamin K p=0,590; vitamin C p=0,534; natrium p=0,491; kalsium p=0,640; zat besi p= 0,323. Hasil uji korelasi asupan energi dengan status gizi p=0,021; karbohidrat p=0,107; protein p=0,020; lemak p=0,32; vitamin A p=0,242; vitamin D p=0,491; vitamin E p=0,587; vitamin K p= 0,600; vitamin C p=0,069; natrium p=0,031; kalsium p=0,077; zat besi p=0,018. Ada hubungan pengetahuan gizi dan makanan dengan status gizi.

This study evaluated differences in the clinical appearance of patients with hepatocellular carcinoma (HCC) based on plasma level and regulation of microRNAs (miRNA-29c, miRNA-21, and miRNA-155). The observational-analytical study with a cross-sectional design was conducted on 36 HCC patients and 36 healthy controls. The blood samples were collected from 2 Province Hospitals (Dr. Sardjito Hospital and Prof. Dr. Margono Soekarjo Hospital) for HCC and the Blood Bank Donor of the Indonesian Red Cross for 36 healthy controls. These blood samples were treated as follows: plasma isolation, RNA isolation, cDNA synthesis, quantification by qRT-PCR using a sequence-specific forward primer, and normalization of miRNA using housekeeping-stably miRNA-16. There were only 27 HCC patients with complete clinical variables (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), platelet count, albumin, C-reactive protein (CRP), and cholinesterase (ChE)) that were able to analyses for regulation miRNAs based on its fold change expression miRNA target. All 27 HCC subjects were follow-up until 3-years of monitoring for their overall survival. The miRNA plasma expression was analyzed by Bio-Rad CFX 96 Manager software to determine the cycle of quantification, followed by the calculation of expression levels using Livak’s methods. Data were analyzed using STATA 11.0, with a significant value of p<0.05. The miRNAs expression of HCC subjects were lower than that healthy control subjects in miRNA-29c (down-regulation 1.83-fold), higher than that healthy control subjects in miRNA 21 and miRNA-155 (up-regulation, 1.74-fold; 1.55-fold) respectively. NLR, CRP, ChE, and platelet count showed a significant difference in miRNA-29c regulation, though neutrophil count showed a significant difference in miRNA-21 and miRNA-155 regulation (p<0.05). Conclusion: Plasma biomarkers: miRNA-21 and miRNA-155 might be potential biomarkers as onco-miR in HCC subjects, while miRNA-29c might act as a tumor suppressor. Significant evidence was identified with clinical progression based on the regulation of miRNAs, which was consistent with miRNA -29c.

Prevalensi dismenore di Indonesia masih tergolong tinggi yaitu sebesar 64, 25% yang dapat diatasi dengan terapi farmakologi maupun non farmakologi. Terapi non farmakologi diantaranya yaitu Self Hypnosis dan Senam Yoga yang mampu meningkatkan hormon endorphin sehingga dapat mengurangi rasa nyeri dan kecemasan saat menstruasi. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi self hypnosis dan senam yoga terhadap tingkat nyeri dan kecemasan saat menstruasi. Desain penelitian Quasy Experiment dengan pre test post test control design. Populasi sejumlah 32 mahasiswa Prodi DIII Kebidanan Universitas Ngudi Waluyo yang mengalami dismenore primer dan menggunakan tehnik purposive sampling sehingga didapatkan ada 32 responden terbagi menjadi 2 kelompok yaitu intervensi dan kontrol masing-masing 16 responden. Penelitian dilakukan selama 3 siklus menstruasi sejak bulan Mei-Juli 2018. Hasil penelitian kemudian diuji dengan uji t test didapatkan hasil bahwa ada perbedaan tingkat nyeri dan kecemasan pada kelompok intervensi dan kontrol.