There are several types of wounds with their own healing properties. The latest innovation in wound management by using occlusive dressings can prevent infections, improve healing time and patient’s comfort. Occlusive dressings are often used as an immediate wound hygiene control and also prevent blood loss until debridement is performed. They are used to protect wounds and surrounding tissue from pathogens and other harmful materials. A good cover depends on the condition around the wound, the person's skills, and the injury's nature. In this article, we provide an insight into the types of polymer materials used clinically in wound dressing and underlying mechanisms between the biomaterial dressings and the body tissue.

Background: Chronic wounds carry financial burdens and increase morbidity and mortality, especially in diabetic ulcers and Hansen's Morbus. More than 50% of chronic ulcers are difficult to heal with regular treatment and require new types of therapy such as the use of secretome of human umbilical cord mesenchymal stem cells (SM-hUCMSC). Methods: This experimental study was carried out to see the effectiveness of using SM-hUCMSC in diabetic ulcers and Hansen's Morbus in four medical facilities (multicentre). The level of active secretion has been measured by default in 10% SM-hUCMSC gel, used as a treatment intervention. The primary outcome is wound healing in terms of the length, width, and extent of the wound. The secondary is the side effects of treatment 2 weeks after administration. Follow-up visits will be scheduled at 1 and 2 weeks posttreatment.Results: Forty-one chronic ulcers successfully followed the study until the end. In patients with chronic ulcers, the mean ulcer length, width, and area were 1.60 (0,50-13,0), 1.3 (0,5-6,0), and 2.21 (0,25-78) cm square, respectively, before interventions and 1 (0-12), 0,8 (0-6,0), and 1 (0-72) square cm after interventions at the second follow-up. The change between the beginning and end of the intervention was significant (p-value <0.05). Conclusion:The use of 10% SM-hUCMSC gel topically has been proven effective in accelerating the process of wound healing, especially chronic ulcers with side effects that are not present in this study.

Introduction: Leprosy is a chronic disease with various manifestations. Leprosy is also known as "The Great Imitator Disease," making this disease quite challenging to detect. Late treatment can cause deformity and disability. Case: A 43 years old man with Hansen's Disease multibacillary leprosy type is newly diagnosed after having a chronic neurotrophic ulcer for years. Discussion: Signs and symptoms of leprosy mimicking other diseases. Diagnosis, according to cardinal sign and the type of classification, must be determined for the necessary treatment. Conclusion: Experience in finding early signs and symptoms of leprosy is essential for diagnosing.

Scabies is a skin disease caused by Sarcoptes Scabiei var. Hominis, tiny mites burrow into the stratum corneum. The World Health Organization has stated that scabies is one of the skin-neglected tropical diseases. This disease is highly contagious, common in tropical developing countries with high density of population, low levels of hygiene, sanitation and economy with limited access to treatment. Scabies has a small but measurable impact on health-related quality of life. To find correlation between the level of knowledge and personal hygiene with the incidence of scabies and the dermatology quality of life at Cempaka Putih Public Health Center. Descriptive and analytic observational cross-sectional with consecutive sampling method. The number of samples are 100 respondents. Data was analyzed using Pearson Correlation Test and Cronbach’s Alpha for its reliability. The hypothesis was analyzed using Chi-Square Test and Fisher’s Exact for the alternative test. Scabies was found in 61% subjects, 36% subjects have good level of knowledge, 82% subjects have good level of hygiene, and 33% felt a major influence on the dermatology quality of life. The significance value between the level of knowledge and personal hygiene with the incidence of scabies (p value) are (p=0.218) and (p=0.107). Meanwhile, the significance value between the level of knowledge and personal hygiene with dermatology quality of life are (p=0.986) and (p=0.002). There is no significant relationship between the level of knowledge and personal hygiene with the incidence of scabies at Cempaka Putih Public Health Center. There is a significant relationship between personal hygiene and dermatology quality of life.  Keywords: Scabies, Level of Knowledge, Personal Hygiene, Dermatology Life Quality Index  ABSTRAK Skabies adalah penyakit kulit yang disebabkan oleh Sarcoptes Scabiei varietas Hominis, tungau kecil yang dapat menggali terowongan dalam stratum korneum. World Health Organization menyatakan bahwa skabies merupakan salah satu penyakit kulit daerah tropis yang terabaikan (Skin Neglected Tropical Diseseases).  Penyakit ini sangat menular, umum terjadi di negara berkembang beriklim tropis dengan kepadatan penduduk yang tinggi, tingkat higinitas, sanitasi dan ekonomi yang rendah serta akses pengobatan yang terbatas. Skabies memiliki dampak kecil namun terukur pada kualitas hidup terkait dengan kesehatan. Mengetahui hubungan antara tingkat pengetahuan dan personal hygiene dengan kejadian skabies dan kualitas hidup dermatologis di Puskesmas Kecamatan Cempaka Putih. Observasional deskriptif dan analitik cross sectional dengan metode consecutive sampling. Jumlah sampel 100 orang. Analisis data menggunakan uji korelasi Pearson serta reliabilitasnya menggunakan Cronbach’s Alpha. Analisis hipotesis menggunakan uji Chi-Square dan uji alternatif Fisher’s Exact Test. Sebanyak 61% subjek menderita skabies, 36% memiliki tingkat pengetahuan baik, 82% subjek memiliki tingkat higinitas baik dan 33% merasakan pengaruh besar terhadap kualitas hidup dermatologis. Nilai signifikasi antara tingkat pengetahuan dan personal hygiene terhadap kejadian skabies (p value) adalah sebesar (p=0.218) dan (p=0.107). Sementara nilai signifikasi tingkat pengetahuan dan personal hygiene dengan indeks kualitas hidup dermatologis adalah sebesar (p=0.986) dan (p=0.002). Tidak terdapat hubungan bermakna antara tingkat pengetahuan dan personal hygiene dengan kejadian skabies di Puskesmas Kecamatan Cempaka Putih. Terdapat hubungan bermakna antara higinitas personal dengan kualitas hidup dermatologis. Kata Kunci: Skabies, Tingkat Pengetahuan, Personal Hygiene, Indeks Kualitas Hidup Dermatologis