Abstrak Sindrom Ovarium Polikistik (SOPK) merupakan kelainan endokrin dan metabolik pada wanita usia reproduksi. SOPK merupakan kumpulan gejala dari amenore, oligomenore, infertilitas, obesitas, hirsutisme, acne, alopesia, dan akantosis nigrikan. Resistensi insulin diyakini sebagai salah satu penyebab tersering dari SOPK melalui berbagai mekanisme. Tujuan penelitian ini adalah untuk mengetahui hubungan resistensi insulindengan gambaran klinis SOPK. Penelitian ini dilakukan pada pasien SOPK dengan menggunakan studi cross sectional dengan pendekatan retrospektif, yaitu mengumpulkan kejadian masa lalu dari tahun 2009 - 2011, jumlah sampel 105 orang. Analisis statistik yang digunakan adalah uji chi-square. Hasil penelitian didapatkan 33,3% penderita SOPK mengalami resistensi insulin. Berdasarkan gambaran klinis 35,23% amenore, 64,77% oligomenore, 72,04% infertilitas, 50,5% obesitas, 0,95% hirsutisme, acne 20%, alopesia dan akantosis nigrikan0%. Dari 33,3% SOPK dengan resistensi insulin 40% amenore, 60% oligomenore, 71,9% infertilitas, 77,14% obesitas, dan 0% hirsutisme. Berdasarkan hasil uji statistik ditemukan hubungan bermakna antara resistensi insulin dengan obesitas (p<0,05) dan tidak ditemukan hubungan bermakna antara resistensi insulin dengan infertilitas, hirsutisme, dan acne (p>0,05).Kata Kunci: SOPK, resistensi insulin, gambaran klinisAbstract Polycystic Ovary Syndrome (PCOS) is an endocrine and metabolic disorders that is common in reproductive-aged women. PCOS is a group of symptoms, such as amenorrhea, oligomenorrhea, infertility, obesity, hirsutism, acne, alopecia, and achanthosis nigricans. Insulin resistance is believed to be one of the most common causes of PCOS through a various mechanisms. The objective of this study was to find out the relationship between insulin resistance and clinical manifestation of PCOS. This research was done in patients with PCOS using cross sectional study with retrospective approach. Data was collected from 2009-2011, with the sample of 105 patients. This research used statistical analysis, that was chi square test. This research found that  33.3% patients of PCOS have insulin resistance. Based on clinical manifestation found that 35.23% amenorrhea, 64.77% oligomenorrhea, 72.04% infertility, 50.5% obesity, 0.95% hirsutism, 20% acne, 0% alopecia and achanthosis nigricans. From 33.3% PCOS with insulin resistance, 40% amenorrhea, 60%  oligomenorrhea, 71.9% infertility, 77.14% obesity, and 0% hirsutism. The results showed that there is a significant relationship between insulin resistance and obesity (p<0.05) and no significant reslationship between insulin resistance and infertility, hirsutism, and acne (p>0.05).Keyword: PCOS, insulin resistance, clinical manifestation

AbstrakMenopause merupakan waktu penghentian menstruasi secara permanen yang terjadi setelah hilangnya aktivitas ovarium. Saat ini jumlah wanita usia menopause meningkat seiring dengan peningkatan usia harapan hidup. Studi tentang menopause sangat penting, terutama terkait akibat yang akan terjadi pasca menopause seperti penyakit kardiovaskuler dan osteoporosis. Tujuan penelitian ini adalah menentukan usia menopause alami dan menganalisis hubungannya terhadap jumlah paritas pada wanita di Kelurahan Bandar Buat Padang. Penelitian  ini merupakan  studi analitik cross-sectional terhadap wanita usia 45-60 tahun yang berada di Kelurahan Bandar Buat Padang. Pengumpulan data dilakukan melalui  wawancara dengan  menggunakan kuesioner  di rumah atau di tempat kerja mereka. Hasil penelitian menunjukan 69 wanita yang diteliti didapatkan rata-rata jumlah paritas adalah 3,663 dengan jumlah paritas 1 dan terbanyak memiliki 10 orang anak. Rata-rata usia menopause responden dalam penelitian ini adalah usia 50,65 tahun dengan usia termuda 46 tahun dan tertua 58 tahun. Terdapat hubungan yang signifikan antara jumlah paritas dan usia menopause di Kelurahan Bandar Buat  dengan hasil p< 0,01.Kata kunci: menopause, jumlah paritas, penyakit kardiovaskuler, osteoporosis AbstractMenopause is the permanent cessation of menstruation period that occurs after the loss of ovarian activity. Currently, the number of women of menopausal age increases as the increase in life expectancy. The study of menopause is very important, especially related to the consequences that will occur after the menopause such as cardiovascular disease and osteoporosis. The objective of this study was to determine the age of natural menopause and analyze its relationship on the amount of parity in the Village Bandar Buat Padang. This study was a cross-sectional analytic study to women aged 45-60 years  in the Village of Bandar Buat Padang. Data collected through interviews using a questionnaire at home or at their workplace. The results showed that from 69 women obtained the average number of parity at the menopausal women is 3.663 with the lowest mumber of parity 1 and the highest had 10 children. The average age of menopause respondents in this study was 50.65 years of age, the youngest is 46 years old and the oldest is 58 years.  There is a significant relationship between the number of parity and the age of menopause in the Village District of Bandar Buat Lubuk Kilangan the result of p =0.00 ( p<0.01).Keywords: menopause, total parity, cardiovascular disease, osteoporosis

AbstrakRantai dingin sangat penting dipertahankan selama distribusi dan penyimpanan vaksin untuk mencapai efektifitas vaksin. Petugas Imunisasi di layanan primer harus memiliki pengetahuan dan pemahaman yang baik mengenai transportasi dan penyimpanan vaksin. Penelitian dilaksanakan di seluruh puskesmas Kota Padang pada Maret 2014, dengan menggunakan desain cross sectional. Jumlah sampel adalah 21petugas imunisasi dengan teknik total sampling. Pengumpulan data dilakukan dengan menggunakan kuesioner dan observasi. Hasil penelitian didapatkan responden dengan pengetahuan yang baik tentang penyimpanan dan transportasi vaksin sebesar 61,9% dan praktik penyimpanan dan transportasi vaksin di Puskesmas yang baik sebesar 61,9%. Berdasarkan uji statistik, didapatkan tidak adanya hubungan umur, tingkat pendidikan, masa kerja dan pengalaman pelatihan petugas imunisasi dengan praktik penyimpanan dan transportasi vaksin di Puskesmas tetapi terdapat hubungan pengetahuan petugas dengan praktik. Berdasarkan hasil penelitian disimpulkan bahwa tidak terdapatnya hubungan karakteristik petugas imunisasi dengan praktik penyimpanan dan transportasi vaksin dan terdapatnya hubungan bermakna antara pengetahuan petugas dengan praktik penyimpanan dan transportasi vaksin di Puskesmas Kota Padang. AbstractPreserving the cold chain during distribution and storage is critical to achieve the effectiveness of the vaccine.Immunization workers in primary health care should have a good knowledge and understanding about the handling and storage of the vaccine. The experiment was conducted in all health centers Padang in 2014 March, using a crosssectional design. Total samples 21 immunization workers with total sampling. The data was collected using questionnaires and observation. The results showed respondents with good knowledge about vaccine storage and handling of 61.9% and vaccine storage and handling practices in health centers of 61.9% which is good. Based on statistical tests, found no rellation between age, education, years of working and training experience of immunization workers with vaccine storage and handling practices in health care but a significant correlation between knowledge with practice. Based on the results of the study concluded that the absence of the relations between characteristic immunization workers with vaccine storage and handling practices and a significant correlation between knowledge workers with practical storage and handling of vaccines at the health center of Padang.

One of the government’s efforts through the Millennium Development Goals (MDGs) in 2010 in reducing the infantmortality rate in Indonesia is improving infants nutrition and promote exclusive breastfeeding early breastfeedinginitiation. Early initiation of breastfeeding has many benefits for both mother and baby. This study aimed to comparemeconium spending time and meconium color change and the incidence of physiologic jaundice in infants whoreceived and did not receive early breastfeeding initiation (IMD). This study was a cross sectional analytical studyconducted at the Achmad Mochtar Hospital Bukittinggi. Forty-two maternity patients divided into two groups thatprovide IMD and unprovide IMD group to her baby. In each group assessed first meconium spending time in minutes,the time change meconium original colour of dark green to yellow and counted since birth in hours and the incidenceof physiologic jaundice in infants. All babies kept getting breastfeeding. There were no significant differences in themean time the first meconium spending time in both groups (131.42 minutes and 163.33 minutes, p> 0.05). There aresignificant differences in the mean time meconium colour changes from dark green to yellow (50.14 hours and 94.36hours, p <0.05). Early initiation of breastfeeding also lowers the incidence of physiological jaundice were significantly(p <0.05). Early initiation of breastfeeding did not affect spending time first meconium but accelerate meconiumcolor changes from dark green to yellow. Early initiation of breastfeeding also lowers the incidence of neonataljaundice.

AbstrakKontrasepsi hormonal dapat mempengaruhi jumlah hitung folikel antral masih menjadi kontroversi. Penelitian ini menilai efek kontrasepsi hormonal melalui parameter ultrasonografi terhadap 32 pengguna kontrasepsi hormonal dan 32 pengguna kontrasepsi non hormonal. Penelitian ini dilakukan dengan metode uji klinis prospektif di Poliklinik Ginekologi RSUP Dr. M. Djamil Padang pada bulan Maret sampai Juli 2014. Subjek dibagi menjadi dua kelompok dan dilakukan pemeriksaan USG transvaginal pada bulan pertama dan kedua pada siklus menstruasi hari 2-4. Analisis statistik untuk menilai kemaknaan menggunakan paired t test pada SPSS 18.0 for windows. Tidak terdapat hubungan yang bermakna jumlah hitung folikel antral bulan pertama dan kedua (P > 0.05) akibat variasi tren perubahan folikel pada kedua kelompok. Tidak terdapat hubungan yang bermakna gain score jumlah hitung folikel antral bulan kedua dengan bulan pertama pada kedua kelompok (P > 0.05). Tidak terdapat perbedaan bermakna jumlah hitung folikel antral pada pengguna kontrasepsi hormonal dan non hormonal, Tidak terdapat perbedaan bermakna gain score jumlah hitung folikel antral pada pengguna kontrasepsi hormonal dan non hormonal. AbstractIt remains controversial whether antral follicle count is influenced by hormonal contraception.. This study quantified the effect of hormonal contraception on sonographic ovarian reserve markers in 32 users and 32 non-users of hormonal contraception. This was a prospective clinical trial study and has been performed in gynecology Department of M. Djamil Hospital Padang, primary health care March to July 2014. Samples then divided into two groups, group A was users of non hormonal contraception and group B was users of hormonal contraception. On day 2-4 of the menstrual cycle transvaginal sonography was performed and measured repeatedly in the same individual before and after the use of one cycle oral contraceptives (for group B), and on first month and second month (for group A). Statistical analysis to assess significance using the unpaired t test and chi square on SPSS 18.0 for windows. There was no significant association of the antral follicle count between users than non-users of hormonal contraception (p>0,05). There were no significant difference of antral follicle count between users and non-users of hormonal contraception. There were no significant difference of gain score of antral follicle count between users and non-users of hormonal contraception.