Toxoplasmosis represents one of the most widespread zoonosis caused by T. gondii parasite, an intracellular protozoan with a worldwide distribution. This disease infects all warm-blooded animals, including humans. The current study aimed to detect the role of some functional hormones among pregnant women suffering from Toxoplasma gondii. The study was carried out during the period from October 2021 to first February 2022 on (200) pregnant women who attended to various governmental hospitals in Maysan province of Iraq with their ages ranged from (19-35) years. Venous blood samples were collected from all pregnant women enrolled in this study. The results showed that of the total (200) pregnant women, 97(48.50%) had positive IgG antibodies to toxoplasmosis, while 103(51.50%) had negative IgG antibodies to toxoplasmosis. The results also exhibited that of the total (200) pregnant women, 11(5.50%) had positive IgM antibodies to toxoplasmosis, while 189(94.50%) had negative IgM antibodies to toxoplasmosis. In patients with IgG positive antibodies, the mean luteinizing hormone (LH) level was (2.69 ±0.33), and in patients with IgG negative antibodies, the mean LH level was (2.23 ±0.24), while in patients with IgG positive antibodies, the mean follicular stimulating hormone (FSH) level was (5.48 ±1.35),,,,
High glucose levels in patients with diabetes are associated with increased plasma levels of soluble adhesion molecules. They could explain that the patients with diabetes mellitus will require the development of premature atherosclerosis related to hyperglycemia or hyperinsulinemia and that it not only affects vascular endothelium but also contributes to the development of microvascular complications. This study aimed to evaluate the serum concentration of VCAM-1 in type 1 diabetes mellitus patients with and without cardiovascular disease. Also, investigation the association of insulin levels, duration of diabetes, and HbA1C with VCAM-1. Include in this study a total of 60 types 1 diabetic patient. According to characteristic laboratory investigations and electrocardiogram (ECG), they were subdivided into two groups (G1) 30 T1DM patients without cardiovascular disease and (G2) 30 T1DM patients with cardiovascular disease in addition to 30 healthy subjects as a control group (G3). All subjects measured the levels of fasting blood glucose FBG, glycated hemoglobin HbA1c, and insulin levels, and VCAM-1 were also determined by ELISA technique. This study shows a highly significant difference in the average diabetic profile between G1 and G2 compared to the control group and found that VCAM-1 level was significantly higher among diabetic patients than the control group. Also, there was a significant negative correlation of VCAM-1 with the levels of FBG, HbA1c in diabetic patients G1 and G2. While insulin had a positive correlation in G1 but correlated negatively in G2
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