Multihop smart grid is built on the basis of an integrated and high-speed communication network. Through the application of advanced sensing and measurement technology, equipment technology, control method, and advanced decision support system technology, the goal of reliable, safe, economic, efficient, environment-friendly, and safe use of the power grid is realized. In order to solve the problem of excessive demand for power supply, new energy power generation and demand response are proposed. According to the above background, the demand side economic scheduling problem is a complex optimization problem, which is difficult to be solved by ordinary algorithms. The adaptive global search algorithm based on a genetic algorithm can better solve complex optimization problems. The genetic algorithm proposed in this paper can effectively manage a large number of controllable loads in the selected area. The algorithm minimizes the cost and peak to the average ratio by changing the load. Home users can arrange their maximum load when the price is low. The peak load of residential buildings decreased from 98.5 kw/h to 90 kw/h, and the peak load decreased by about 7.53%. Through appropriate load dispatching, users minimize the daily electricity charge, which is reduced from 1352 yuan to 1245 yuan per day, and the daily electricity charge is reduced by about 7.25%. In addition, the advanced measurement, communication, and control means under the framework of the smart grid also play a key role in promoting all aspects of demand side management (DSM).