The absorption and transport of umbelliferone, osthole, columbianadin, columbianetin acetate, angelol-A and angelol-B are passive diffusion as the dominating process in Caco-2 cell monolayer model. Umbelliferone, osthole, angelol-A and angelol-B are estimated to be highly absorbed compounds, and columbianadin and columbianetin acetate are estimated to be moderately absorbed compounds. In the Caco-2 cells, osthol and columbianadin appear to accumulate, and columbianetin acetate may be metabolized. The absorption and transport of angelol-B are not influenced by the change of pH and the presence of iodoacetamide or MK571.

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A New Ellagic Acid Derivative from the Fruits of Eucalyptus globulus Labill -[isolation and structure elucidation]. -(GUO, Q.-M.; YANG*, X.-W.; Pharmazie 60 (2005) 9, 708-710; Beijing Med. Univ., Beijing 100083, Peop. Rep. China; Eng.) -A. Forchert 01-206