Introduction: MYH9-related disease (MYH9-RD) is a rare autosomal dominant disorder caused by mutations in MYH9, which is responsible for encoding nonmuscle myosin heavy chains IIA (NMMHCIIA). MYH9-RD is clinically characterized by congenital macrothrombocytopenia, granulocyte inclusions variably associated with the risk of developing progressive sensorineural deafness, cataracts and nephropathy. Patient concerns: A 5-year-old boy had a history of a mild bleeding tendency and chronic thrombocytopenia, first identified at four months of age. No other family members were noted to have similar clinical features or hematologic disorders. Diagnoses: The boy was diagnosed with MYH9-RD. Light microscopic examination of peripheral blood films (Wright-Giemsa stain) showed marked platelet macrocytosis with giant platelets and basophilic Döhle-like inclusions in 83% of the neutrophils. Immunofluorescence analysis disclosed a type II pattern, manifested by neutrophils which contained several circle-to-oval shaped cytoplasmic NMMMHCA-positive granules. Sequencing analysis of MYH9-RD genes was carried out and revealed a novel missense mutation of c.97T>G (p.W33G) in the patient but not in his parents. Intervention: No treatment is necessary. Recognition of MYH9-RD is important to Avoiding unnecessary and potentially harmful treatments. Outcomes: The patient's condition remained stable during the follow-up. Conclusions: As a result of identifying this missense mutation in this particular case, we have added c.97T>G (p.W33G) to the broad spectrum of potential MYH9 mutations.

This extended abstract provides an overview of the environmental liabilities of oil and gas assets, asset retirement obligations (AROs) and environmental reporting requirements under the regulatory regimes in Alberta, in Canada and International Financial Reporting Standards (IFRS). Lifecycle asset liability and environmental management processes are associated with abandonment, remediation and reclamation, decommissioning and closure. Alberta's production of conventional oil and gas and oil sands projects has resulted in increased concerns related to climate changes and environmental liabilities of oilfield assets. More stringent regulatory compliance and standards have been developed and are likely to continue. Operators are responsible for the costs to comply with environmental regulations and take sufficient social responsibilities. The industrial experience of discharging liabilities has indicated that planning at early stages of the operation and managing asset liability bring a reduced cost and risk. Full lifecycle cost-effective and efficient environmental management begins with planning and successful acquisition. The best estimate calculation can be based on internal or external costs, depending on which is most likely.

A 3D model of hydrostatic turntable's oil chamber is established to investigate the lubricants performance with different rheological properties by using FLUENT software and the finite volume method. Newtonian oil and non-Newtonian oil's performance under varied speeds are compared on the large size hydrostatic turntable system considering the temperatureviscosity relationship and pressure-viscosity relationship. The results show that the property of non-Newtonian fluid viscosity influenced by shear rate largely affects the lubricants performance for most oil added polymer additives. Lubricants cannot simply be regarded as Newtonian fluid. The shear thickening non-Newtonian fluid has a better work property. The results are important to design a large size and high-speed hydrostatic support system, choose lubricant oils, and investigate oil film's work properties.