Background: Head and neck cancer is the most common malignancy in Sindh, Pakistan. The type of cancer can be observed in the oral cavity, lips, buccal mucosa, oropharynx, hypopharynx, nasopharynx, the floor of the mouth and hard palate in Sindh. , comprising 56% males and 44% females. The most common site of the head and neck tumors was the oral cavity (58%), followed by the tongue, tonsil, floor of the mouth, gum, hard palate, soft palate, and lips. Other sites of head and neck cancer were hypo-pharynx, nasopharynx, salivary gland, parotid gland, oral-pharynx, and lyrnx. Most patients came in NORIN at stage III and stage IV of their disease and most of them were at the age of 40 -85 years. Most patients were the residents of Nawabshah and neighboring districts. Conclusions: Head and neck malignancy was the most common type of cancer registered in NORIN in the last five years. Because of the lack of awareness, education, and diagnostic facilities, most patients start cancer treatment at later stages of the disease, which makes it very difficult to cure. Smoking and the use of alcohol, Gutka, Supari, Naswar, Man-Pori, etc., are the main causes of head and neck cancer.

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Elevated exposure from background radiations and health hazards for radiation workers have recently grabbed the attention of researchers. This study targeted to measure the background radiation levels in the operating console areas radiation facilities of NORIN, Nawabshah Pakistan. Ten operating consoles of different treatment and diagnostic machines were surveyed using a calibrated RM1001-RD LAMSE radiation monitor for the period of one year periodically and AEDR was calculated using standard formulas. The organ doses were calculated using recommended occupancy and conversion factors. The highest point with increased AEDR was found to be the operating console of cobalt-60 teletherapy machine (0.876 ± 0.03 mSv/yr), while the lowest at the Digital Radiography operating console (0.730 ± 0.03 mSv/yr). The standard error ranged between 0.02-0.03 %. These findings affirm a statistically significant difference in T-test values at a level of significance of 5% (P<0.05). The testes received the maximum dose (0.718 mSv/yr) followed by bonemarrow (0.604 mSv/yr) at Co-60 Teletherapy operating console. Conclusion: Based on these results, it was deduced that radiation levels are well within the permissible radiation limit of 1.0 mSv/yr prescribed by the ICRP and hardly about 37% of UNSCEAR limit of 2.4 mSv/yr. Therefore, all radiation workers are radiologically safe in operating console areas because all radiation protection and regulatory protocols are strictly observed in the working environment. This study eliminates the undue anxiety about the hazardous nature of radiation in the radiation workers of cancer hospitals.

During 05 years period from January 2003 to December 2007,45 cases of Ca. Pancreas were reported to LINAR and only onecase of Pseudo Papillary Tumour of Pancreas is registered. It is a rare, low malignant potential pancreatic tumour. It has unknown pathogenesisand found in young females. We report a case of 24 years old female, who presented with pain in abdomen and low grade fever of 07 monthsduration. Lepratomy and excisional biopsy was done. H/P came as Pseudo Papillary Tumour of Pancreas. At presentation no any L.N. werefound enlarged. Like other malignant pancreatic tumours, this neoplasm does not metastasize. Its definitive treatment is complete surgicalremoval, no any role of chemotherapy because it doesn't metastasized, limited role of radiotherapy in local invasive tumour or in residual mass.