R Braun scite author profile

Clearance mittels Formel oder 24h-Sammelurin?Vor manchen Chemotherapien, insbesondere Cisplatin-haltigen ist die Bestimmung einer Kreatinin-Clearance/GFR notwendig. Ist die Bestimmung mittels Formel (Cockcroft-Gault, MDRD) ausreichend oder ist in jedem Fall eine endogene Kreatinin-Clearance (mit 24h-Sammelurin) anzustreben? Verbessert eine Infusions-!!! therapie während der Sammelperiode die endogene Kreatinin-Clearance? Die ursprüngliche MDRD-Formel kann zur hinreichend zuverlässigen Abschätzung der GFR vor Chemotherapie herangezogen werden -die nach Levey modifizierte nur bedingt. Eine weitere Alternative zum Sammelurin stellt Cystatin C dar.

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R Braun

A histological method for studying the effects of drugs on mediator-induced airway microvascular leakage in rodents

Some evidence for the extraneuronal uptake of rimiterol and its metabolism by catechol-O-methyltransferase in guinea-pig trachealis smooth muscle cells

Vor Chemotherapie: Bestimmung der Kreatinin-Clearance mittels Formel oder 24h-Sammelurin?

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