In this work, the assessment of surface and ground water quality of Palladam Taluk, Tiruppur, district, Tamil Nadu, India were carried out using Geographical Information System (GIS) and Modified National Sanitation Foundation -Water Quality Index (MNSF-WQI). Four samples from surface and twenty seven samples from ground water sources were taken from Palladam Taluk, Tiruppur District. In the current study, the surface and ground water samples were analysed for temperature, pH, dissolved oxygen (DO), electrical conductivity (EC), biological oxygen demand (BOD), turbidity, total dissolved solids (TDS), total hardness (TH), faecal coliforms (FC), total phosphate (TP), total nitrate (TN), chlorides (Cl-), sodium (Na+) and fluoride (F-) ions to investigate the suitability of surface and ground water for drinking and agricultural purposes through Geographic information system (GIS) and modified national sanitation foundation water quality index (MNSF-WQI) technique. The concentrations of TH, TDS, Cl- and Na+ were observed to be above the desirable limit of World Health Organization (WHO) guidelines and Bureau of Indian Standards (BIS). whereas F-, BOD, DO, EC, TP, TN, FC and temperature were within the acceptable limits. The GIS-based WQI map analysis indicated that 45% of the study area having good water quality index and the remaining area showed medium quality water. Dyeing and textile industries in the study area are responsible for deteriorating the quality to medium quality of water which was not appropriate for direct utilization and needed prior treatment. There is no detailed report on assessment of the surface and ground water quality of Palladam Taluk in Tamil Nadu using GIS and MNSF-WQI techniques.