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Cardiac troponins are important indicators of myocardial damage. Recent studies have shown that serum cardiac troponin levels are raised in at least 50% of patients with renal disease. The mechanisms and implications of these findings are discussed.

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RELATION OF EAR CONDITIONS TO BATHING. I [DICAL JKOt 3. Irradiatioil of rabbits with an identical technique, aftei inlfection with virulenit staphylococcus, gives no protectioni. 4. Experimenlts indicate that the results are not due to the productionof vitamins (A or D). This research was carried out in Professor Leonard Ifill's laboratory at tho National Institute for Medical Research, Hampstead. I anm greatly indebted for his kindness, constant advice, and help during the progress of tlleso experiments.

Over a period of six months all reports in the South Tees Health District of serum calcium levels greater than 2.70 mmol/l were extracted and patient records examined to establish the associated diseases and patterns of management. A total of 235 reports were evaluated, and after exclusion of doubtful cases 196 patients were included in the study. No cause had been identified in 57 (29%). Many of these were elderly females in whom hypercalcaemia may have been due to primary hyperparathyroidism, but parathyroid hormone levels had not been measured. Of those in whom a diagnosis had been made, 62 (45%) were associated with malignancy and 50 (36%) with chronic renal failure. 72% of cases of hypercalcaemia reported to general practitioners and 13% of those reported to hospital doctors were not investigated further. Despite the inclusion of serum calcium estimation on routine biochemical profiles, many cases of hypercalcaemia are being ignored or not investigated further. The study emphasizes the need for a reliable screening test for primary hyperparathyroidism.