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This incomplete list of the advantages which toxoid possesses may be supplemented by the statement that results obtained in the vaccination of a group of young adults revealed the fact that the immunizing qualities of this prophylactic were as readily demonstrable in human beings as in experimental animals.Upon the completion of this preliminary work, arrangements were made in a number of centers for more extended use of diphtheria toxoid prepared in the Connaught Laboratories. These further trials, notably in Hamilton, Windsor, and Brantford, Ontario, were eminently successful. Very quickly the use of toxoid spread to other parts of Canada and soon its employment upon a large scale was undertaken. This very satisfactory state of affairs has continued, and in the past 6 years sufficient toxoid for the vaccination of over 1,000,000 persons has been distributed in the Dominion.

lowing paragraph is characteristic of the claims made for Eumictine : "Anti-gonorrhoic by its Santalol, diuretic, urolytic and analgetic by its hexamethylenetetramin (Urotropin) antiseptic and antipyretic by its Salol, Eumictine represents a real therapeutic advance in the scientific treatment of diseases of the urinary passages." Instead of being "a real therapeutic advance" in the treat¬ ment of diseases of the urinary passages, Eumictine presents one of the complex combinations that have long retarded the scientific treatment of these diseases. Eumictine also con¬ flicts with Rules 4 and 8 of the Council. NEED OF UNIFORMITY IN SHAPE AND SIZE OF PROFESSIONAL REPRINTSAND ADVERTISED OBJECTS Tothe Editor:\p=m-\Thereshould be uniformity in the size. shape and arrangement of printed data that the physician may wish to preserve, conveniently file and promptly refer to. This should include (a) reprints of papers and (b) advertising data describing objects that deserve preservation and prompt reference.The object of collectanea is convenience for filing and for reference. I have previously made recommendations to advertisers that they adopt a suitable system whereby descriptive matter, memoranda, etc., could be readily filed. One measure has been extensively adopted, viz., index filing cards of a standard size, 3 by 5, also small, closely printed circulars or descriptive booklets of the same size and containing several pages of outline. The fact is that many physicians now use index filing systems, kept in the drawer of a desk for short case notes, and another for other data.