Background: Global measures are often used to assess employees’ job satisfaction. However, important information is lost when this approach is  adopted. The use of multidimensional approach provides robust information for potential intervention. This study aimed to assess the work facets  predicting the overall single-item job satisfaction measure among teachers in Ibadan, Nigeria. Methods: This was a cross-sectional descriptive study conducted among 476 secondary school teachers selected using a multistage sampling  method. A structured questionnaire was used for data collection while data was analyzed using SPSS version 26. The Minnesota Satisfaction  Questionnaire (MSQ) and a single-item satisfaction measure assessed satisfaction. A linear regression model of the overall job satisfaction was developed. P-value ≤ 0.05 was regarded as statistically significant. Results: The mean age of respondents was 38.1±9.0 years. Majority of respondents were females 263 (55.3%) and married 363 (76.3%). The  respondents expressed above average satisfaction with all work facets except compensation 161 (33.8%) and work conditions 223 (46.8%). The work  facets which significantly predicted overall job satisfaction included: supervision-human relations (β = 0.121: 95% CI = 0.013 to 0.229; p = 0.028);policies & practices (β = 0.111: 95% CI = 0.021 to 0.201; p = 0.016); compensation (β =0.125: 95% CI = 0.035 to 0.214; p = 0.006) and recognition (β = 0.113: 95% CI = 0.006 to 0.220; p = 0.039) Conclusion: Overall job satisfaction was mostly predicted by factors extrinsic to the job, so these could be specifically targeted for interventions to  improve job satisfaction among teachers.