A full-term, female presented on her date of birth with severe pulmonary hypertension (PH) and mitral regurgitation (MR), requiring veno-arterial extracorporeal membrane oxygenation. After the treatment, her PH and MR were resolved with no anatomic abnormality present. We propose a positive feedback loop of PH causing right ventricular dilation and interventricular septal shifts, worsening MR, and elevated left atrial, and potentially pulmonary, pressures.
Outcome measures included gross tissue coagulation, tumor growth and immunohistochemical characterization (cell positivity/ high power field) of markers of dendritic cells (DCs) (CD11c), M1 macrophages (CD68), and cytotoxic T-cells (CD8+) in the periablational rim and in untreated tumor two high power fields away from the ablation zone. Results: Adjuvant lip-GM-CSF with RFA markedly increased periablational CD8+ cell infiltration at 3d and 7d (113.3
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