Die aus Kornstärke leicht zugängliche Lö‐Anhydro‐β‐D‐ glucopyranose (Ia) ergibt über das Ditosylat (Ib) ein Gemisch der Allylether (II) und (III), von denen ersterer zur Verbindung (IV) umgesetzt wird.
In order to synthesize the spiroacetal moiety of milbemycins and avermectins, the required lactones (V) and the required acetylene (XIIIa) are prepared as shown.
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