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Another reason for selecting the thyroid gland was that previous observations by one of us (2) had determined a number of conditions which are associated with rest and activity respectively of the gland. Thus, exposure to cold and the injection of ,B-tetrahydronaphthylamin produce an intense activity of the gland, while a resting condition is induced by exposure to a hot environment, and by thyroid feeding. The increased activity of the gland on exposure to cold and after injection of tetrahydronaphthylamin manifests itself by an intense congestion of the interalveolar and the intra-alveolar capillaries and by a disappearance of the colloid from the alveoli. A figure illustrating this condition

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