The results of renal transplantation in boys treated for posterior urethral valves were evaluated and compared with a matched control group. Patient and graft survival was equal in both groups, although serum creatinine levels were slightly higher in the posterior urethral valves group. Postoperative complications, such as urinary tract infections, occurred more frequently in the posterior urethral valves group. Urodynamic evaluation was performed before transplantation in 11 of 20 patients. Adequate treatment of bladder dysfunction, such as poor compliance and/or hyperreflexia, is essential in diminishing the risks of secondary graft damage due to severe bladder dysfunction.

The medical records were reviewed of 127 consecutive patients with esophageal atresia alone and with tracheoesophageal fistula. Systematical genitourinary tract examination in 112 patients showed anomalies in 24 (21.4 per cent). A survey of the literature on this subject is given. Of 8 patients with the VATER association renal involvement was found in 6. The results of urinary tract imaging by excretory urography and ultrasonography are compared to each other. Prompt and appropriate genitourinary tract examination by physical examination, urinalysis, serum creatinine levels and ultrasonography or excretory urography is recommended as a standard in all children with esophageal atresia, with further investigations ordered if indicated by the results of the studies.

The prenatal diagnosis, management and outcome of an hereditary obstructive uropathy is presented. Serial ultrasonic assessment of the fetal urinary tract was carried out from the early second trimester onward. Slight bilateral hydronephrosis as a first sign of obstructive uropathy was only established as late as 30 weeks of gestation. On the basis of weekly ultrasound scans, a conservative approach was adopted. In view of fetal maturity, labour was induced at 36 weeks resulting in the vaginal delivery of a male infant with moderate bilateral hydronephrosis. Neonatally, anuria developed due to bilateral obstruction of the ureters as a result of increasing bladder wall hypertrophy due to urethral valves. A bilateral uretero-cutaneostomy was carried out. The infant so far develops normally, and renal function is normal for age. Women at risk for fetal obstructive uropathy should have ultrasonic monitoring throughout pregnancy.

Summary— Renographic studies under standardised conditions of maximal diuresis provoked by hypotonic saline infusion and frusemide were used in 17 patients with dilatation of the upper urinary tract in order to distinguish between obstructed and non‐obstructed urinary tracts. Of the six patients who were obstructed on clinical and X‐ray evidence only three showed an obstructed pattern on the renographic curves after maximal diuresis. After operation these three patients showed improvement in both renographic curve and functional images of the renal parenchyma. A new method of identifying the parenchymal area is described.