Objective: The present investigation is an attempt to an ethnomycological mushroom survey carried out among the paliyar tribals of five settlements in Sirumalai hills. Daldinia concentrica, mushroom reported by the tribals for the wound healing activity was evaluated in vivo in rat model. Methods:The indigenous information of the tribal people was collected through personal interviews during field trips and also the ethno reported mushroom Daldinia concetrica was analysed for its phytochemical constituents by Harborne method and its potential wound healing activity in Albino Wistar rats by excision wound model. Results:The exploration revealed that 92% of the respondents consume mushroom as food and four mushrooms are used in ethnomedicine in the study area namely, Daldinia concentrica, Calvatia gigantean, Termitomyces microcarpus and Podaxis pistillaris. Daldinia concentrica for wound healing, is the first ethnomycological report, thus the further study on Daldinia revealed that the mushroom sample consists of alkaloid 0.97±0.07 mg/kg, flavanoid 2.97±0.12 mg/kg, phenol 0.32±0.01 mg/kg, tannin 0.17±0.02 mg/kg, terpenoid 0.07±0.01 mg/kg and saponin 0.09±0.02 mg/kg; and it's in vivo wound healing activity was found to be outstanding around 75-87% compared to that of the commercial ointment neosporin. Conclusion:We believe that wound healing activity of Daldinia mushroom was due to the synergestic effect of phytochemicals present in them. Our results throw in the insight of the traditional use of mushrooms in various treatments.

Introduction: C. curviflora, an important ethno-medicinal plant used by the Kurichia local people in Western Ghats region of Wayanad is yet to be explored pharmacologically. It is used as paste on the body of cattle and birds for curing skin diseases. Objectives: To characterize the pharmacochemical features and to study the acaricidal effect of ethanolic extract of C. curviflora on engorged female ticks of R. (B.) annutatus. Methods: The pharmaco-chemical features such as physico-chemical, proximate, phytochemical, fluorescence, and HPTLC profiling were carried out using standard techniques. The pulverized leaves were subjected to soxhlet extraction using ethanol. The ethanolic extract at different concentrations (10% to 1.25%) was tested against ticks using adult immersion test (AIT). Result: The preliminary phytochemical investigation showed high contents of saponins, alkaloids and flavonoids. The HPTLC profiling of ethanolic extract showed the presence of 14 polyvalent components. Based on AIT, the extract at 10% revealed 43.76% of inhibition of fecundity (IF) and 29.16%

Folk remedies practiced by the tribes of Kolli Hills of Eastern Ghats, Tamil Nadu, India were documented. Around 30 folk remedies for snake bite, 18 for scorpion sting and 4 for dog bite were reported in this study. Details of the plants used for snake bite, scorpion sting and dog bite with local name, parts used and methods of preparation, dosage and the mode of administration were discussed.

Objective: To determine the antioxidant and anti-inflammatory activity of myco-synthesized silver nanoparticle (AgNP) from Pleurotus florida.Methods: Fresh mushrooms were collected, processed, and the AgNPs were synthesized using standard reducing agent 1 mM of silver nitrate. The characteristics of synthesized particles were confirmed using ultraviolet, Fourier transmission infrared, X-ray diffraction, and energy dispersive X-ray analysis. These nanoparticles were subjected for antioxidant activity through 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay and anti-inflammatory activity using bovine serum albumin denaturation assay, respectively, and the percentage of inhibition of AgNPs was calculated with standard error mean. Results:The AgNPs were recorded the absorbance band at 410 nm was the particle size of 20-50 nm with a rod in shape. In DPPH assay the antioxidant activity was recorded as 96.2% with 50% inhibitory concentration (IC50) value of 85 µg/ml. In anti-inflammatory activity, the activity was recorded as 92.10±0.005% and IC50 value was recorded as 100 µg/ml. Conclusion:The results indicated the significant antioxidant and anti-inflammatory activity of AgNPs from P. florida. Hence, further in vivo studies are focused to confirm the anticancer and anti-inflammatory activities.

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