R. Munger scite author profile

Insulin resistance appears to be the primary determinant of the modifications to VLDL subfraction concentrations. Our results suggest a continuum of impaired insulin action on VLDL, ranging from that in healthy persons to that in patients with type 2 diabetes, in which obese patients occupy a transition state. Insulin resistance may also play a role in detrimental modifications to the LDL profile by allowing the development of hypertriglyceridemia.

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Progressive defect of insulin action on glycogen synthase in obesity and diabetes

Golay

Munger

Assimacopoulos-Jeannet

et al. 2002

Metabolism

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R. Munger

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Progressive defect of insulin action on glycogen synthase in obesity and diabetes

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