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Key indicators: single-crystal X-ray study; T = 296 K; mean (C-C) = 0.003 A ˚ ; R factor = 0.054; wR factor = 0.144; data-to-parameter ratio = 21.5. The title 1,2,4-triazole compound, C 13 H 11 N 5 OSÁC 3 H 7 NO, crystallizes as a 1:1 dimethylformamide (DMF) solvate. The main molecule exists in a trans configuration with respect to the acyclic C N bond. An intramolecular C-HÁ Á ÁS hydrogen bond generates an S(6) ring motif. In the synthesis, a proton is transferred from the O atom of a hydroxy group to the quinoline group N atom. The essentially planar triazole ring and quinoline ring system [maximum deviations of 0.001 (2) and 0.013 (2) A ˚ , respectively] form a dihedral angle of 5.86 (9). In the crystal structure, molecules of (E)-4-[(2-hydroxy-3-quinolyl)methyleneamino]-3-methyl-1H-1,2,4-tria-zole-5(4H)-thione are linked into R 2 2 (8) centrosymmteric dimers via N-HÁ Á ÁO hydrogen bonds. These dimers are further linked into an extended three-dimensional structure by the DMF solvent molecules via intermolecular N-HÁ Á ÁO and C-HÁ Á ÁO hydrogen bonds. The crystal structure is consolidated by two different intermolecular-interactions [centroid-centroid distances = 3.6593 (12) and 3.6892 (12) A ˚ ]. Related literature For general background to and applications of 1,2,4-triazole derivatives, see: Al-Soud et al. Experimental Crystal data C 13 H 11 N 5 OSÁC 3 H 7 NO M r = 358.42 Monoclinic, P2 1 =c a = 7.2374 (1) A ˚ b = 23.4970 (4) A ˚ c = 10.8214 (2) A ˚ = 107.820 (1) V = 1751.97 (5) A ˚ 3 Z = 4 Mo K radiation = 0.21 mm À1 T = 296 K 0.45 Â 0.27 Â 0.19 mm Data collection Bruker SMART APEXII CCD area-detector diffractometer Absorption correction: multi-scan (SADABS; Bruker, 2005) T min = 0.912, T max = 0.962 27543 measured reflections 5088 independent reflections 2909 reflections with I > 2(I) R int = 0.044

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Reaction of the isatins (I) with thiosemicarbazide (II) yields the derivatives (III).